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Nicole Creasey; Patty Leijten; Marieke S. Tollenaar; Marco P. Boks; Geertjan Overbeek – Child Development, 2024
This study investigated associations of the Incredible Years (IY) parenting program with children's DNA methylation. Participants were 289 Dutch children aged 3-9 years (75% European ancestry, 48% female) with above-average conduct problems. Saliva was collected 2.5 years after families were randomized to IY or care as usual (CAU). Using an…
Descriptors: Foreign Countries, Parent Child Relationship, Child Behavior, Behavior Problems
Parade, Stephanie H.; Ridout, Kathryn K.; Seifer, Ronald; Armstrong, David A.; Marsit, Carmen J.; McWilliams, Melissa A.; Tyrka, Audrey R. – Child Development, 2016
Accumulating evidence suggests that early adversity is linked to methylation of the glucocorticoid receptor (GR) gene, "NR3C1," which is a key regulator of the hypothalamic-pituitary-adrenal axis. Yet no prior work has considered the contribution of methylation of "NR3C1" to emerging behavior problems and psychopathology in…
Descriptors: Preschool Children, Behavior Problems, Genetics, Psychopathology
Sage, Cindy; Burgio, Ernesto – Child Development, 2018
Mobile phones and other wireless devices that produce electromagnetic fields (EMF) and pulsed radiofrequency radiation (RFR) are widely documented to cause potentially harmful health impacts that can be detrimental to young people. New epigenetic studies are profiled in this review to account for some neurodevelopmental and neurobehavioral changes…
Descriptors: Child Development, Genetics, Telecommunications, Handheld Devices
Connolly, John J.; Glessner, Joseph T.; Hakonarson, Hakon – Child Development, 2013
Efforts to understand the causes of autism spectrum disorders (ASDs) have been hampered by genetic complexity and heterogeneity among individuals. One strategy for reducing complexity is to target endophenotypes, simpler biologically based measures that may involve fewer genes and constitute a more homogenous sample. A genome-wide association…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Genetic Disorders
Marceau, Kristine; Horwitz, Briana N.; Narusyte, Jurgita; Ganiban, Jody M.; Spotts, Erica L.; Reiss, David; Neiderhiser, Jenae M. – Child Development, 2013
Studies of adolescent or parent-based twins suggest that gene-environment correlation (rGE) is an important mechanism underlying parent-adolescent relationships. However, information on how parents' and children's genes and environments influence correlated parent "and" child behaviors is needed to distinguish types of rGE. The present…
Descriptors: Foreign Countries, Genetics, Environment, Correlation
Belsky, Jay; Pluess, Michael – Child Development, 2013
Data from 508 Caucasian children in the NICHD Study of Early Child Care and Youth Development shows that the DRD4 (but not 5-HTTLPR) polymorphism moderates the effect of child-care quality (but not quantity or type) on caregiver-reported externalizing problems at 54 months and in kindergarten and teacher-reported social skills at kindergarten and…
Descriptors: Child Development, Personality, Infants, Genetics
Naumova, Oksana Yu.; Hein, Sascha; Suderman, Matthew; Barbot, Baptiste; Lee, Maria; Raefski, Adam; Dobrynin, Pavel V.; Brown, Pamela J.; Szyf, Moshe; Luthar, Suniya S.; Grigorenko, Elena L. – Child Development, 2016
This study attempted to establish and quantify the connections between parenting, offspring psychosocial adjustment, and the epigenome. The participants, 35 African American young adults (19 females and 16 males; age = 17-29.5 years), represented a subsample of a 3-wave longitudinal 15-year study on the developmental trajectories of low-income…
Descriptors: Child Rearing, Adjustment (to Environment), Psychological Patterns, Social Development
Davies, Patrick T.; Cicchetti, Dante – Child Development, 2014
This study tested the 5-HTTLPR gene as a moderator in the relation between maternal unresponsiveness and child externalizing symptoms in a disadvantaged, predominantly Black sample of two hundred and one 2-year-old children and their mothers. Using a multimethod, prospective design, structural equation model analyses indicated that maternal…
Descriptors: Genetics, Mothers, Parent Child Relationship, Affective Behavior
McGuire, Shirley; Segal, Nancy L. – Child Development, 2013
Research suggests that sibling--peer connections are important for understanding adolescent problem behaviors. Using a novel behavioral genetic design, the current study investigated peer network overlap in 300 child--child pairs (aged 7-13 years) in 5 dyad types: monozygotic (MZ), dizygotic twins, full siblings (FSs), friend pairs, and virtual…
Descriptors: Siblings, Behavior Problems, Genetics, Children
Brody, Gene H.; Beach, Steven R. H.; Philibert, Robert A.; Chen, Yi-Fu; Murry, Velma McBride – Child Development, 2009
A randomized prevention design was used to investigate a moderation effect in the association between a polymorphism in the "SCL6A4"("5HTT") gene at 5-HTTLPR and increases in youths' risk behavior initiation. Participation in the Strong African American Families (SAAF) program was hypothesized to attenuate the link between 5-HTTLPR status and risk…
Descriptors: Prevention, At Risk Persons, Adolescents, Genetics
Leve, Leslie D.; Kerr, David C. R.; Shaw, Daniel; Ge, Xiaojia; Neiderhiser, Jenae M.; Scaramella, Laura V.; Reid, John B.; Conger, Rand; Reiss, David – Child Development, 2010
To further the understanding of the effects of early experiences, 9-month-old infants were observed during a frustration task. The analytical sample was composed of 348 linked triads of participants (adoptive parents, adopted child, and birth parent[s]) from a prospective adoption study. It was hypothesized that genetic risk for externalizing…
Descriptors: Mothers, Pregnancy, Infants, Genetics
Saudino, Kimberly J.; Plomin, Robert – Child Development, 2007
Although a negative association between hyperactivity and academic achievement is well documented, little is known about the genetic and/or environmental mechanisms responsible for the association. The present study explored links between parent and teacher ratings of hyperactive behavior problems and teacher-assessed achievement in a sample of…
Descriptors: Behavior Problems, Hyperactivity, Genetics, Academic Achievement

Cleveland, H. Harrington; Wiebe, Richard P.; van den Oord, Edwin J. C. G.; Rowe, David C. – Child Development, 2000
Examined influences on children's behavior problems in households defined by marital status and sibling relatedness. Found that genetic influences accounted for 81 to 94 percent of mean-level difference in behavior problems between two-parent/full sibling, and the mother-only/half sibling groups. Shared environmental influences accounted for 67 to…
Descriptors: Behavior Problems, Children, Comparative Analysis, Environmental Influences

Deater-Deckard, Kirby – Child Development, 2000
Examined environmental and gene-environment processes linking parenting (affect, control, responsiveness) and preschoolers' behavioral adjustment difficulties (noncompliance, conduct problems). Found that estimates of shared environmental variance and mediation were greatest for observational data, and estimates of child genetic variance and…
Descriptors: Adjustment (to Environment), Behavior Problems, Child Behavior, Compliance (Psychology)