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Direct linkZwaigenbaum, Lonnie; Bryson, Susan E.; Brian, Jessica; Smith, Isabel M.; Sacrey, Lori; Armstrong, Vickie; Roberts, Wendy; Szatmari, Peter; Garon, Nancy; Vaillancourt, Tracy; Roncadin, Caroline – Child Development, 2021
The objectives were to characterize behavioral signs of autism spectrum disorder (ASD) in younger siblings of diagnosed children (high-risk; HR) and examine classification features of the Autism Observation Scale for Infants (AOSI). Participants (501 HR and 180 low-risk [LR]) were assessed between 6 and 18 months using the AOSI and at age 3 for…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Infant Behavior
Plate, Samantha; Yankowitz, Lisa; Resorla, Leslie; Swanson, Meghan R.; Meera, Shoba Sreenath; Estes, Annette; Marrus, Natasha; Cola, Meredith; Petrulla, Victoria; Faggen, Aubrey; Pandey, Juhi; Paterson, Sarah; Pruett, John R., Jr.; Hazlett, Heather; Dager, Stephen; St. John, Tanya; Botteron, Kelly; Zwaigenbaum, Lonnie; Piven, Joseph; Schultz, Robert T.; Parish-Morris, Julia – Child Development, 2022
Infant vocalizations are early-emerging communicative markers shown to be atypical in autism spectrum disorder (ASD), but few longitudinal, prospective studies exist. In this study, 23,850 infant vocalizations from infants at low (LR)- and high (HR)-risk for ASD (HR-ASD = 23, female = 3; HR-Neg = 35, female = 13; LR = 32, female = 10; 80% White;…
Descriptors: Infants, Toddlers, Verbal Communication, Autism
Connolly, John J.; Glessner, Joseph T.; Hakonarson, Hakon – Child Development, 2013
Efforts to understand the causes of autism spectrum disorders (ASDs) have been hampered by genetic complexity and heterogeneity among individuals. One strategy for reducing complexity is to target endophenotypes, simpler biologically based measures that may involve fewer genes and constitute a more homogenous sample. A genome-wide association…
Descriptors: Autism, Pervasive Developmental Disorders, Genetics, Genetic Disorders
Developmental Trajectories in Children with and without Autism Spectrum Disorders: The First 3 Years
Landa, Rebecca J.; Gross, Alden L.; Stuart, Elizabeth A.; Faherty, Ashley – Child Development, 2013
Retrospective studies indicate 2 major classes of autism spectrum disorder (ASD) onset: early and later, after a period of relatively healthy development. This prospective, longitudinal study examined social, language, and motor trajectories in 235 children with and without a sibling with autism, ages 6-36 months. Children were grouped as: ASD…
Descriptors: Pervasive Developmental Disorders, Autism, Comparative Analysis, Longitudinal Studies
Webb, Sara Jane; Jones, Emily J. H.; Merkle, Kristen; Venema, Kaitlin; Greenson, Jessica; Murias, Michael; Dawson, Geraldine – Child Development, 2011
Individuals with autism spectrum disorder (ASD) show differences in face processing abilities from early in development. To examine whether these differences reflect an atypical versus delayed developmental trajectory, neural responses to familiar and unfamiliar faces in twenty-four 18- to 47-month-old children with ASD were compared with…
Descriptors: Autism, Developmental Delays, Pervasive Developmental Disorders, Visual Perception
Beaudet, Arthur L. – Child Development, 2013
Chromosomal microarray analysis (CMA) has emerged as a powerful new tool to identify genomic abnormalities associated with a wide range of developmental disabilities including congenital malformations, cognitive impairment, and behavioral abnormalities. CMA includes array comparative genomic hybridization (CGH) and single nucleotide polymorphism…
Descriptors: Genetics, Genetic Disorders, Developmental Disabilities, Identification
Oppenheim, David; Koren-Karie, Nina; Dolev, Smadar; Yirmiya, Nurit – Child Development, 2009
In the current study (a) maternal insightfulness into the experience of the child and (b) resolution with respect to the child's diagnosis and their associations with children's security of attachment were examined in a sample of 45 preschoolers (mean age = 49 months) with autism spectrum disorders (ASD). It was hypothesized that mothers who were…
Descriptors: Mothers, Autism, Pervasive Developmental Disorders, Experience
Van Hecke, Amy Vaughan; Lebow, Jocelyn; Bal, Elgiz; Lamb, Damon; Harden, Emily; Kramer, Alexis; Denver, John; Bazhenova, Olga; Porges, Stephen W. – Child Development, 2009
Few studies have examined whether familiarity of partner affects social responses in children with autism. This study investigated heart rate regulation (respiratory sinus arrhythmia [RSA]: The myelinated vagus nerve's regulation of heart rate) and temporal-parietal electroencephalogram (EEG) activity while nineteen 8- to 12-year-old children with…
Descriptors: Autism, Familiarity, Medicine, Interpersonal Competence
