The learning management system (LMS) is claimed to be a crucial strategy for creating successful e-learning and teaching methods, enhancing students' learning satisfaction and achieving academic outcomes. Although the Indonesia Open University has implemented e-learning innovation through LMS in higher education, it has not gained popularity. Hence, the present research aimed to investigate the updated DeLone and McLean information system (IS) success model on the effectiveness of LMS implementation, focusing on system quality, information quality, service quality, perceived usefulness and user satisfaction. A total of 386 respondents from undergraduate and postgraduate programs were selected through stratified random sampling. Subsequently, research data were collected through online survey questionnaires administered to students enrolled at the Indonesia Open University. Structural equation modeling with "AMOS version 24" software was deployed to analyze data and test hypothesis. Findings revealed that the updated DeLone and McLean IS success model had a positive and significant influence on the effectiveness of LMS. Therefore, the top-level management of the Indonesia Open University and decision-makers in the Indonesian government could provide a better LMS practice environment infrastructure utilizing the updated DeLone and McLean IS success model.