The thrifty phenotype and fetal overnutrition hypotheses are two developmental hypotheses that originated from the "developmental origins of health and disease" (DOHaD) perspective. The DOHaD posits that exposures experienced prenatally and early in life may influence health outcomes through altering form and function of internal organs…

This study examines interactions of heritable influences, prenatal substance use, and postnatal parental warmth and hostility on the development of conduct problems in middle childhood for boys and girls. Participants are 561 linked families, collected in 2 cohorts, including birth parents, adoptive parents, and adopted children. Heritable…

This study tested the association between multiple prenatal and postnatal early life factors and adolescent sexual orientation in a longitudinal birth cohort. Factors included birth weight, gestational age, parental age at birth, number of older brothers and sisters, breastfeeding, maternal anxiety/depression, family socioeconomic position,…

Postnatal maternal depression is associated with poorer child emotional and behavioral functioning, but it is unclear whether this occurs following brief episodes or only with persistent depression. Little research has examined the relation between postnatal anxiety and child outcomes. The present study examined the role of postnatal major…

This study examined infants' early visual attention (at 1 month of age) and social engagement (4 months) as predictors of their later joint attention (12 and 18 months). The sample (n = 325), drawn from the Maternal Lifestyle Study, a longitudinal multicenter project conducted at 4 centers of the National Institute of Child Health and Human…

Clinically meaningful behavior problems are thought to be present beginning in the early toddler years, yet few studies have investigated correlates of behavior problems assessed before age 2 years. The current study investigated the direct and interactive contributions of early infant and caregiver characteristics thought to play an important…

Our goal in the present study was to examine the effects of maternal smoking during pregnancy on infant self-regulation, exploring birth weight as a mediator and sex as a moderator of risk. A prospective sample of 218 infants was assessed at 6 months of age. Infants completed a battery of tasks assessing working memory/inhibition, attention, and…

Examined gender differences in cognitive outcome in children born prematurely who had incurred early cerebral lesions and in a high-risk comparison group. A significant gender difference in cognitive recovery was observed in the lesion group. Girls outperformed boys on standardized intelligence tests. No gender differences were observed in the…

In a study of 24 preterm and 24 full-term infants at 8 months, infants who reacted to a novel stimulus with increased vagal tone showed more focused examination and exhibited greater exploratory play range than those whose vagal tone decreased with the stimulus. (LB)

Investigates the relationship between the perinatal hormonal environment and the development of cognitive sex differences. Compares 25 upper class women aged 14 to 24 who were exposed prenatally to diethylstilbestrol (DES) and their unexposed sisters. Subjects show a more masculine pattern of lateralization than their sisters but are similar in…

Prenatal cocaine and opiate exposure are thought to subtly compromise social and emotional development. The authors observed a large sample of 236 cocaine-exposed and 459 nonexposed infants (49 were opiate exposed and 646 nonexposed) with their mothers in the face-to-face still-face paradigm. Infant and maternal behaviors were microanalytically…

Examined longitudinally the relationship between biological and social risk factors and aggressive behavior patterns among high-risk Australian adolescents in three groups: early-onset persistent aggression, adolescent-onset aggression, and nonaggressive behavior groups. Findings revealed that the interaction of biological and social risk factors…

Examines long-term effects of Cesarean birth using a stratified mixed-race random sample of Baltimore school children who began first grade in 1982. Looks at the beliefs and expectations of both the parents and children of Cesarean births. Higher expectations were the norm in comparison to children of non-Cesarean birth experiences. (Author/RWB)