Studies indicated Web 2.0 technologies can support learning. Then, integration of innovation may create concerns among teachers because of the innovative features. In this study, the innovation refers to Web 2.0 technology integration into instruction. To help pre-service teachers make the best use of the innovation in their future instruction, it is essential to examine the patterns of their concerns about integrating Web 2.0 technologies into their practice. About 350 future teachers participated in the study during the spring semester of 2012 in a northern university of Taiwan. The Stages of Concerns (SOC) Questionnaire was adopted to assess seven stages of concern: awareness, informational, personal, management, consequence, collaboration and refocusing. The findings of this study indicated the pre-service teachers' concerns as a whole were most intense respectively in the stages of informational, personal, and collaboration. A few implications were indicated for teacher education programs to alleviate the concerns. [For the full proceedings, see ED562107.]