Evidences showed that students' chemistry learning outcomes were still low. One of the causes was the chemistry practicums carried out so far were traditional chemistry practicums. Therefore, it needed to be reoriented towards the practicum. Thus, this study aimed to investigate the effect of green chemistry practicums on students' learning outcomes on the topic of chemical equilibrium shifts. This study used two classes, namely one class as a control group and another class as an experimental group. Each class consisted of 40 students, respectively. The traditional chemistry practicums were taught to the control group, while the green chemistry practicums were taught to the experimental group. Analysis of covariance was used to test a hypothesis at a significance level of 5%. The results of the study showed that there was a significant difference in the learning outcomes of students. The methods of green chemistry practicums were better in improving the learning outcomes than those of traditional chemistry practicums. It was recommended that senior high school teachers can apply these methods to improve students' learning outcomes.