There is heightened concern about the need to provide equal access to education for children with disability. Children with disability form part of the many disadvantaged groups who are denied access to education. A qualitative approach with descriptive design was used to study the perceptions of parents in the Wa West district of the Upper West Region of Ghana, on the education of their children with disability. Twenty (20) parents of children with disability were purposively selected and interviewed. The data collected were analyzed using thematic analysis. Findings showed that factors such as parents' understanding of disability, cost-benefit issues, awareness/knowledge levels and concerns about safety/security determined parental decisions to send or not to send children with disability to school. The study recommended that there should be comprehensive public education for parents with children with disability as well as opinion leaders in various communities about the potentials of children with disability.