Cluster analysis of data from 166 children with autistic spectrum disorders revealed 4 subtypes with differences in behavioral and cognitive areas. The four subtypes include a typically autistic group, a low-functioning group, a high-functioning group (Asperger syndrome/schizoid), and a hard-to-diagnose group with mild/moderate retardation and a…

Subjects with autism (n=36) were assigned a simple "reach, grasp, and place" task. Comparison with nonautistic children who had mental retardation and younger normally developing children found that the autistic subjects had problems in executing goal-directed motor acts even in very simple situations, suggesting an independent and marked…

Comparison of children and adolescents with Fragile X Syndrome (n=18) or autism (n=18) for changes in cognitive ability and adaptive behavior over 9 years found steeper decreases in IQ scores among Fragile X subjects with older autistic subjects autism exhibiting stable test-retest scores. Comparative declines in adaptive behavior scores were…

Evaluation of social-cognitive skills in 23 young children with autism or other developmental delays found tests involving others' attention were more difficult for children with autism than tests involving others' behavior. However, the typical developmental pattern of first sharing, then following, and then directing attention or behavior was…

The communicative behaviors of 6 girls with Rett syndrome (ages 2-13) were evaluated. Findings indicated that all subjects were at a preintentional level of communication, which was consistent with their profound intellectual disability and their lack of demonstration of "means-end" behavior beyond Piagetian Sensorimotor Stage III.…

This study sought to differentiate pervasive developmental disorder not otherwise specified (PDDNOS) from similar nonautistic disorders on the basis of a cognitive deficit, theory of mind (ToM), which is the ability to infer mental states in others, a deficit highly prevalent in autism, a disorder similar to PDDNOS. Results suggest that children…

The study of affect comprehension in 15 children with pervasive developmental disorders (ages 7-10) and normal children matched for mental age found that the disabled children were impaired on affect matching compared to the controls and were impaired on face and affect matching relative to their own performance on object matching. (Author/DB)

A method for empirical classification of autistic and autisticlike children, based on behavior observations of 35 males and 11 females (ages 4-28 years) was examined. Factor and cluster analysis indicated four subtypes, characterized by perseverative thinking and play, motor disturbances, schizotypal/schizoid features, and anxiety and negativism.…

Parents of 42 children (ages 2-32) with Lesch-Nyhan disease were questioned concerning the subjects' behavior patterns. Grouping of responses into nine categories of cognitive skills indicated that only one boy showed any significant cognitive impairment. Despite evidence of good cognitive and emotional skills, subjects were academically delayed,…