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Decades of Progress in the Psychopharmacology of Autism Spectrum Disorder
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Henneberry, Erin; Lamy, Martine; Dominick, Kelli C.; Erickson, Craig A. – Journal of Autism and Developmental Disorders, 2021
Recent decades have been marked by a wave drug treatment research in autism spectrum disorder (ASD). This work has resulted in improved ability to treat commonly occurring behavioral challenges associated with ASD including most prominently irritability marked by aggression, self-injurious behavior, and severe tantrums. While treatment of…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Pharmacology
Epidemiological Screening for the Risk of Mental, Behavioral and Developmental Disorders, Including Autism, in Early Childhood: Data for Russia 2017-2019
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Simashkova, N. V.; Ivanov, M. V.; Boksha, I. S.; Klyushnik, T. P.; Zozulya, S. A.; Sharlay, I. A. – Journal of Autism and Developmental Disorders, 2023
We aimed to screen children aged 18-48 months in the general population of nine Russian regions for risk of mental, behavioral and developmental disorders (MBDDs) including autism spectrum disorders (ASD) using an original screening tool. The prevalence of the risk for MBDDs is 1307:10,000 (13.07%), the prevalence of clinically verified cases of…
Descriptors: Epidemiology, Screening Tests, Risk, Mental Disorders
Behavioral Phenotypes and Comorbidity in 3q29 Deletion Syndrome: Results from the 3q29 Registry
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Rebecca M. Pollak; Michael Mortillo; Melissa M. Murphy; Jennifer G. Mulle – Journal of Autism and Developmental Disorders, 2025
3q29 deletion syndrome (3q29del) is associated with a significantly increased risk for neurodevelopmental and neuropsychiatric disorders. However, the full spectrum of behavioral phenotypes associated with 3q29del is still evolving. Individuals with 3q29del (n = 96, 60.42% male) or their guardian completed the Achenbach Child or Adult Behavior…
Descriptors: Genetic Disorders, Neurodevelopmental Disorders, Behavior Disorders, Symptoms (Individual Disorders)
Advances in Our Understanding of Behavioral Intervention: 1980 to 2020 for Individuals Diagnosed with Autism Spectrum Disorder
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Leaf, Justin B.; Cihon, Joseph H.; Ferguson, Julia L.; Milne, Christine M.; Leaf, Ronald; McEachin, John – Journal of Autism and Developmental Disorders, 2021
There are three branches of science of behavior analysis [i.e., experimental analysis of behavior, behavior analysis, and applied behavior analysis (ABA)]. ABA can be defined as a systematic approach to understanding behavior of social interest. For the past 40 plus years, researchers have evaluated ABA and ABA based procedures (e.g., behavioral…
Descriptors: Autism, Pervasive Developmental Disorders, Applied Behavior Analysis, Behavior Disorders
An Australian Cross-Sectional Survey of Parents' Experiences of Emergency Department Visits among Children with Autism Spectrum Disorder
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Garrick, Alice; Lee, Marie L.; Scarffe, Carrington; Attwood, Tony; Furley, Kirsten; Bellgrove, Mark A.; Johnson, Beth P. – Journal of Autism and Developmental Disorders, 2022
Parents of children with ASD who had attended an Australian emergency department (ED; n = 421) completed a questionnaire relating to their experiences in the ED, including (1) child's reason for presentation and existing comorbidities, (2) quality of care during the visit (3) child's behaviour during visit, e.g. sensory responses to the ED…
Descriptors: Foreign Countries, Children, Autism, Pervasive Developmental Disorders
Brief Report: Emotional and Behavioral Problems among Young Children with ASD--An Exploratory Study of ADOS E-Codes and Child Characteristics
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Galligan, Megan Ledoux; Heyman, Michelle; Bolourian, Yasamin; Stavropoulos, Katherine; Blacher, Jan – Journal of Autism and Developmental Disorders, 2022
Emotional and behavioral problems (EBPs), such as anxiety, overactivity, and aggression, can influence the diagnosis of autism spectrum disorder (ASD). The gold standard diagnostic tool for ASD, the "Autism Diagnostic Observation Schedule--Second Edition," includes three items ("E-codes") for EBPs that are frequently associated…
Descriptors: Young Children, Autism Spectrum Disorders, Behavior Problems, Behavior Disorders
Relative Frequency of Psychiatric, Neurodevelopmental, and Somatic Symptoms as Reported by Mothers of Children with Autism Compared with ADHD and Typical Samples
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Mayes, Susan D.; Calhoun, Susan L.; Baweja, Raman; Waschbusch, Daniel A. – Journal of Autism and Developmental Disorders, 2021
No study has analyzed the relative occurrence of a broad range of symptoms reported by mothers of children with autism, ADHD-Combined, and ADHD-Inattentive and typical controls. Mothers rated 1436 children with autism, 1056 with ADHD without autism, and 186 controls, 2-17 years, on 41 internalizing, externalizing, neurodevelopmental, and somatic…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Mothers
Time Trends in Diagnostics and Clinical Features of Young Children Referred on Suspicion of Autism: A Population-Based Clinical Cohort Study, 2000-2010
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Avlund, Sara Højslev; Thomsen, Per Hove; Schendel, Diana; Jørgensen, Meta; Clausen, Loa – Journal of Autism and Developmental Disorders, 2021
The present study aimed to explore clinical trends in the period 2000-2010, along with discriminating clinical factors for autism spectrum disorder (ASD), in young children suspected of ASD. The following trends were observed: (1) a rise in referrals including an increase in referrals among language-abled children, (2) an increase in children…
Descriptors: Trend Analysis, Clinical Diagnosis, Autism, Pervasive Developmental Disorders
The Implications of Parent-Reported Emotional and Behavioral Problems on the Modified Checklist for Autism in Toddlers
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Christopher, Kourtney; Bishop, Somer; Carpenter, Laura Arnstein; Warren, Zachary; Kanne, Stephen – Journal of Autism and Developmental Disorders, 2021
Studies have shown that Autism Spectrum Disorder (ASD) screening and diagnostic instruments may be affected by the presence of emotional and behavior problems (EBPs). This study assessed the impact of EBPs on the Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT-R/F). Participants included 290 children, 18-48 months of age,…
Descriptors: Parent Attitudes, Emotional Disturbances, Behavior Disorders, Autism
DNA Methylation of the Oxytocin Receptor across Neurodevelopmental Disorders
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Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry