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Crawford, Hayley; Karakatsani, Efthalia; Singla, Gursharan; Oliver, Chris – Journal of Autism and Developmental Disorders, 2019
Self-injurious and aggressive behaviors are common in fragile X syndrome (FXS). However, little is known about the persistence of these behaviors and associated risk markers. We established the prevalence and persistence of self-injurious and aggressive behaviors over eight years in males with FXS, and associations with risk markers. Results…
Descriptors: Self Destructive Behavior, Aggression, Males, Genetic Disorders
Staal, Wouter G.; de Krom, Mariken; de Jonge, Maretha V. – Journal of Autism and Developmental Disorders, 2012
Recently the "DRD3" gene has been associated with ASD in two independent samples. Follow up analysis of the risk allele of the SNP rs167771 in 91 subjects revealed a significant association with a specific type of repetitive behavior: the factor "insistence on sameness" (IS) derived from the Autism Diagnostic Interview. This risk allele was…
Descriptors: Behavior Patterns, Autism, Genetics, Genetic Disorders