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Hammock, Ron G.; And Others – Journal of Autism and Developmental Disorders, 1995
Clozapine, a neuroleptic drug, was used to complete a 93-week double-blind crossover trial with a 40-year-old male having profound mental retardation and sensory impairments and displaying self-injurious behavior (SIB) patterns. Findings suggest that clozapine could be an effective pharmacological intervention for some cases of SIB. (DB)
Descriptors: Adults, Behavior Change, Case Studies, Drug Therapy

Elliott, Reed O., Jr.; And Others – Journal of Autism and Developmental Disorders, 1994
Six adults with both autism and moderate/profound mental retardation were assessed in a controlled environment for changes in frequency of maladaptive and stereotypic behaviors following nonexercise activities, general motor training activities, and aerobic exercise. Although antecedent aerobic exercise reduced undesirable behaviors, general motor…
Descriptors: Adults, Aerobics, Autism, Behavior Change

Handen, Benjamin L.; Johnson, Cynthia R.; Lubetsky, Martin – Journal of Autism and Developmental Disorders, 2000
Thirteen children (ages 5-11) with autism and symptoms of attention-deficit hyperactivity disorder participated in a double-blind, placebo-controlled crossover study of methylphenidate. Eight subjects responded positively, decreasing their hyperactivity. Ratings of stereotypy and inappropriate speech also decreased, however, no changes were found…
Descriptors: Attention Deficit Disorders, Autism, Behavior Change, Behavior Modification