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Brief Report: Emotional and Behavioral Problems among Young Children with ASD--An Exploratory Study of ADOS E-Codes and Child Characteristics
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Galligan, Megan Ledoux; Heyman, Michelle; Bolourian, Yasamin; Stavropoulos, Katherine; Blacher, Jan – Journal of Autism and Developmental Disorders, 2022
Emotional and behavioral problems (EBPs), such as anxiety, overactivity, and aggression, can influence the diagnosis of autism spectrum disorder (ASD). The gold standard diagnostic tool for ASD, the "Autism Diagnostic Observation Schedule--Second Edition," includes three items ("E-codes") for EBPs that are frequently associated…
Descriptors: Young Children, Autism Spectrum Disorders, Behavior Problems, Behavior Disorders
DNA Methylation of the Oxytocin Receptor across Neurodevelopmental Disorders
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Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Comprehensive Psychometric Analysis of the Eyberg Child Behavior Inventory in Children with Autism Spectrum Disorder
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Jeter, Kathryn; Zlomke, Kimberly; Shawler, Paul; Sullivan, Maureen – Journal of Autism and Developmental Disorders, 2017
Many assessment measures have only been validated for one specific diagnostic population, which is costly and reduces the clinical utility of assessments. The Eyberg Child Behavior Inventory (ECBI) is one popular measure designed to assess disruptive behavior problems in youth. The ECBI has sound psychometric properties in typically developing…
Descriptors: Psychometrics, Behavior Problems, Child Behavior, Measures (Individuals)
Relationship of the Acoustic Startle Response and Its Modulation to Emotional and Behavioral Problems in Typical Development Children and Those with Autism Spectrum Disorders
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Takahashi, Hidetoshi; Komatsu, Sahoko; Nakahachi, Takayuki; Ogino, Kazuo; Kamio, Yoko – Journal of Autism and Developmental Disorders, 2016
Auditory hyper-reactivity is a common sensory-perceptual abnormality in autism spectrum disorders (ASD), which interrupts behavioral adaptation. We investigated acoustic startle response (ASR) modulations in 17 children with ASD and 27 with typical development (TD). Compared to TD, children with ASD had larger ASR magnitude to weak stimuli and…
Descriptors: Autism, Pervasive Developmental Disorders, Auditory Stimuli, Emotional Response
Brief Report: A Comparison of Indirect versus Experimental Strategies for the Assessment of Pica
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Wasano, Lauren C.; Borrero, John C.; Kohn, Carolynn S. – Journal of Autism and Developmental Disorders, 2009
We conducted functional analyses of pica for three individuals with varying levels of intellectual disabilities. In addition, two indirect assessment instruments (the "Motivational Assessment Scale [MAS]", and the "Questions About Behavioral Function [QABF]") were also administered to both the parent and teacher of the child…
Descriptors: Mental Retardation, Behavior Disorders, Reinforcement, Functional Behavioral Assessment
Autism Symptoms in Attention-Deficit/Hyperactivity Disorder: A Familial Trait which Correlates with Conduct, Oppositional Defiant, Language and Motor Disorders
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Mulligan, Aisling; Anney, Richard J. L; O'Regan, Myra; Chen, Wai; Butler, Louise; Fitzgerald, Michael; Buitelaar, Jan; Steinhausen, Hans-Christoph; Rothenberger, Aribert; Minderaa, Ruud; Nijmeijer, Judith; Hoekstra, Pieter J.; Oades, Robert D.; Roeyers, Herbert; Buschgens, Cathelijne; Christiansen, Hanna; Franke, Barbara; Gabriels, Isabel; Hartman, Catharina; Kuntsi, Jonna; Marco, Rafaela; Meidad, Sheera; Mueller, Ueli; Psychogiou, Lamprini; Rommelse, Nanda; Thompson, Margaret; Uebel, Henrik; Banaschewski, Tobias; Ebstein, Richard; Eisenberg, Jacques; Manor, Iris; Miranda, Ana; Mulas, Fernando; Sergeant, Joseph; Sonuga-Barke, Edmund; Asherson, Phil; Faraone, Stephen V.; Gill, Michael – Journal of Autism and Developmental Disorders, 2009
It is hypothesised that autism symptoms are present in Attention-Deficit/Hyperactivity Disorder (ADHD), are familial and index subtypes of ADHD. Autism symptoms were compared in 821 ADHD probands, 1050 siblings and 149 controls. Shared familiality of autism symptoms and ADHD was calculated using DeFries-Fulker analysis. Autism symptoms were higher…
Descriptors: Siblings, Autism, Hyperactivity, Attention Deficit Disorders
Commentary: Considerations on the Characterization and Treatment of Self-Injurious Behavior.
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Ernst, Monique – Journal of Autism and Developmental Disorders, 2000
This commentary uses self-injurious behavior to illustrate the approach of the functional analysis of behavior as a guide to rational treatment strategies for individuals with autism, and to show that the characteristics of the clinical presentations can provide clues for underlying mechanisms that can be used for research and treatment. (Contains…
Descriptors: Adults, Autism, Behavior Disorders, Behavior Problems
Repetitive Thoughts and Behavior in Pervasive Developmental Disorders: Treatment with Serotonin Reuptake Inhibitors.
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McDougle, Christopher J.; Kresch, Laura E.; Posey, David J. – Journal of Autism and Developmental Disorders, 2000
Results from two studies indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in children with autism. A study of the selective SRI fluvoxamine found it to be significantly better than placebo for reducing repetitive…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children
Commentary: Considerations on the Pharmacological Treatment of Compulsions and Stereotypies with Serotonin Reuptake Inhibitors in Pervasive Developmental Disorders.
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Gordon, C. T. – Journal of Autism and Developmental Disorders, 2000
This commentary discusses study results that indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in treating repetitive or ritualized behaviors in children with autism. The need for concurrent genetic and biochemical…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children
Pharmacological Treatment of Mood Disturbances, Aggression, and Self-Injury in Persons with Pervasive Developmental Disorders.
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King, Bryan H. – Journal of Autism and Developmental Disorders, 2000
This article reviews the psychopharmacological treatment of aggression, mood disturbances, and self-injurious behavior in persons with autistic disorder. It highlights the use of dopaminergic drugs, serotonergic drugs, opioidergic drugs, adrenergic drugs, thymoleptic drugs, and glutamatergic drugs for their potential utility in treating…
Descriptors: Adults, Aggression, Behavior Disorders, Behavior Problems