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Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial
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González-Domenech, Pablo José; Díaz Atienza, Francisco; Pablos, Carlos García; Soto, María Luisa Fernández; Martínez-Ortega, José María; Gutiérrez-Rojas, Luis – Journal of Autism and Developmental Disorders, 2020
The use of alternative interventions, such as gluten-free and casein-free (GFCF) diets, is frequent due to limited therapies for Autism Spectrum Disorder (ASD). Our aims were to determine the influence of a GFCF diet on behavior disorders in children and adolescents diagnosed with ASD and the potential association with urinary beta-casomorphin…
Descriptors: Behavior Disorders, Dietetics, Children, Adolescents
DNA Methylation of the Oxytocin Receptor across Neurodevelopmental Disorders
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Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Clinical Outcomes of Behavioral Treatments for Pica in Children with Developmental Disabilities
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Call, Nathan A.; Simmons, Christina A.; Mevers, Joanna E.; Alvarez, Jessica P. – Journal of Autism and Developmental Disorders, 2015
Pica is a potentially deadly form of self-injurious behavior most frequently exhibited by individuals with developmental and intellectual disabilities. Research indicates that pica can be decreased with behavioral interventions; however, the existing literature reflects treatment effects for small samples (n = 1-4) and the overall success of such…
Descriptors: Self Destructive Behavior, Developmental Disabilities, Mental Retardation, Behavior Disorders
Brief Report: Avoidance Extinction as Treatment for Compulsive and Ritual Behavior in Autism
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Wolff, Jason J.; Hupp, Susan C.; Symons, Frank J. – Journal of Autism and Developmental Disorders, 2013
Treatment options for maladaptive repetitive behaviors associated with autism are limited. This is particularly so for ritual and compulsive forms of repetitive behavior, which commonly interfere with adaptive activities and may cause distress to individuals with autism and their families. The present study assessed an avoidance extinction…
Descriptors: Autism, Anxiety Disorders, Behavior Disorders, Repetition
Specialized Inpatient Psychiatry for Serious Behavioral Disturbance in Autism and Intellectual Disability
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Siegel, Matthew; Milligan, Briana; Chemelski, Bruce; Payne, David; Ellsworth, Beth; Harmon, Jamie; Teer, Olivia; Smith, Kahsi A. – Journal of Autism and Developmental Disorders, 2014
Psychiatric hospitalization of children with autism spectrum disorder and/or intellectual disability is common, however, the effectiveness of this intervention is largely unknown. Thirty-eight clinically-referred children 8-19 years old admitted to a specialized inpatient psychiatry unit were assessed by a consistent caregiver on the Aberrant…
Descriptors: Children, Hospitalized Children, Autism, Pervasive Developmental Disorders
A Longitudinal Study of the TEACCH Program in Different Settings: The Potential Benefits of Low Intensity Intervention in Preschool Children with Autism Spectrum Disorder
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D'Elia, Lidia; Valeri, Giovanni; Sonnino, Fabiana; Fontana, Ilaria; Mammone, Alessia; Vicari, Stefano – Journal of Autism and Developmental Disorders, 2014
We conducted a longitudinal study of 30 preschool children with autism spectrum disorders (ASDs) to evaluate the potential benefits of the Treatment and Education of Autistic and related Communication Handicapped Children (TEACCH). Fifteen children following a low intensity TEACCH program were assessed four times for autism severity, adaptive…
Descriptors: Autism, Pervasive Developmental Disorders, Preschool Children, Outcomes of Treatment
Risperidone for Aggression and Self-Injurious Behavior in Adults with Mental Retardation.
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Cohen, Seth A.; Ihrig, Kristin; Lott, Rex S.; Kerrick, Jill M. – Journal of Autism and Developmental Disorders, 1998
Describes the use of risperidone in eight adult patients with moderate to profound mental retardation and markedly aberrant behaviors. Risperidone in these individuals was associated with significant reduction in aggression and self-injurious behavior. Side effects were primarily those of sedation and restlessness. (Author/CR)
Descriptors: Adults, Aggression, Behavior Change, Behavior Disorders
Haloperidol Treatment of Trichotillomania in a Boy with Autism and Mental Retardation.
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Ghaziuddin, M.; And Others – Journal of Autism and Developmental Disorders, 1991
The report describes the successful treatment of trichotillomania (compulsive hair pulling) in a mentally retarded 11-year-old boy with autism and severe mental retardation. Administration of haloperidol resulted in complete cessation of hair pulling which reappeared when the dosage was decreased and ceased again when dosage was reestablished. (DB)
Descriptors: Autism, Behavior Change, Behavior Disorders, Case Studies
Repetitive Thoughts and Behavior in Pervasive Developmental Disorders: Treatment with Serotonin Reuptake Inhibitors.
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McDougle, Christopher J.; Kresch, Laura E.; Posey, David J. – Journal of Autism and Developmental Disorders, 2000
Results from two studies indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in children with autism. A study of the selective SRI fluvoxamine found it to be significantly better than placebo for reducing repetitive…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children
Commentary: Considerations on the Pharmacological Treatment of Compulsions and Stereotypies with Serotonin Reuptake Inhibitors in Pervasive Developmental Disorders.
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Gordon, C. T. – Journal of Autism and Developmental Disorders, 2000
This commentary discusses study results that indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in treating repetitive or ritualized behaviors in children with autism. The need for concurrent genetic and biochemical…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children
Use of Functional Analysis Methodology in the Evaluation of Medication Effects.
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Crosland, Kimberly A.; Zarcone, Jennifer R.; Lindauer, Steven E.; Valdovinos, Maria G.; Zarcone, Troy J.; Hellings, Jessica A.; Schroeder, Stephen R. – Journal of Autism and Developmental Disorders, 2003
The atypical antipsychotic medication risperidone was evaluated using a double-blind, placebo-controlled design to treat destructive behavior in two males (ages 6 and 24) with autism. Destructive behavior during the demand condition was significantly reduced during the medication phases, whereas it continued to occur to obtain tangible items and…
Descriptors: Adult Education, Aggression, Autism, Behavior Disorders
Brief Report: Clonazepam Behavioral Side Effects with an Individual with Mental Retardation.
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Kalachnik, John E.; Hanzel, Thomas E.; Sevenich, Robert; Harder, Stuart R. – Journal of Autism and Developmental Disorders, 2003
This article describes an individual (age 49) with mental retardation who experienced behavioral exacerbation associated with clonazepam prescribed at 2 mg/day to treat aggression, self-injurious behavior, property destruction, and screaming. When clonazepam was reduced and discontinued, these behaviors significantly decreased from 3.1% of…
Descriptors: Adult Education, Adults, Aggression, Behavior Disorders
Pharmacological Treatment of Mood Disturbances, Aggression, and Self-Injury in Persons with Pervasive Developmental Disorders.
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King, Bryan H. – Journal of Autism and Developmental Disorders, 2000
This article reviews the psychopharmacological treatment of aggression, mood disturbances, and self-injurious behavior in persons with autistic disorder. It highlights the use of dopaminergic drugs, serotonergic drugs, opioidergic drugs, adrenergic drugs, thymoleptic drugs, and glutamatergic drugs for their potential utility in treating…
Descriptors: Adults, Aggression, Behavior Disorders, Behavior Problems