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Assessing Child Life Specialists' Management of Challenging Behaviors in Autistic Pediatric Patients
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Kaitlyn Schenk; Amy A. Weimer; Katherine Rice Warnell – Journal of Autism and Developmental Disorders, 2025
Given that autistic children are hospitalized at higher rates than neurotypical peers, it is important to understand the autism-specific preparedness of healthcare providers. Certified Child Life Specialists (CCLSs) play a crucial role in pediatric hospitalizations by providing socioemotional support and coping strategies. The present study…
Descriptors: Autism Spectrum Disorders, Children, Pediatrics, Patients
Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations
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Niccolò Butti; Emilia Biffi; Romina Romaniello; Alessandra Finisguerra; Enza Maria Valente; Sandra Strazzer; Renato Borgatti; Cosimo Urgesi – Journal of Autism and Developmental Disorders, 2025
This study tested the feasibility and efficacy of a Virtual Reality (VR) social prediction training (VR-Spirit) specifically designed for patients with congenital cerebellar malformation. The study is a randomised controlled trial in which 28 cerebellar patients aged 7-25 yo were randomly allocated to the VR-Spirit or to a control intervention in…
Descriptors: Computer Simulation, Prediction, Interpersonal Competence, Children
Physician Perspectives on Severe Behavior and Restraint Use in a Hospital Setting for Patients with Autism Spectrum Disorder
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Salvatore, Giovanna L.; Simmons, Christina A.; Tremoulet, Patrice D. – Journal of Autism and Developmental Disorders, 2022
Hospitals, with many features that can evoke severe behavior in patients with autism spectrum disorder (ASD), often use restraint as a behavior management strategy. Prior research on restraint in patients with ASD has primarily focused on children or specific departments. Twenty-five physicians and medical trainees from an urban teaching hospital…
Descriptors: Physicians, Medical Students, Health Personnel, Patients
A Randomized, Placebo-Controlled, Blinded, Crossover, Pilot Study of the Effects of Dextromethorphan/Quinidine for the Treatment of Neurobehavioral Symptoms in Adults with Autism
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Chez, Michael; Kile, Shawn; Lepage, Christopher; Parise, Carol; Benabides, Bobbie; Hankins, Andrea – Journal of Autism and Developmental Disorders, 2020
Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…
Descriptors: Outcomes of Treatment, Randomized Controlled Trials, Pilot Projects, Drug Therapy
Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems--A Retrospective Feasibility Study
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Aran, Adi; Cassuto, Hanoch; Lubotzky, Asael; Wattad, Nadia; Hazan, Esther – Journal of Autism and Developmental Disorders, 2019
Anecdotal evidence of successful cannabis treatment in autism spectrum disorder (ASD) are accumulating but clinical studies are lacking. This retrospective study assessed tolerability and efficacy of cannabidiol-rich cannabis, in 60 children with ASD and severe behavioral problems (age = 11.8 ± 3.5, range 5.0-17.5; 77% low functioning; 83% boys).…
Descriptors: Behavior Problems, Autism, Pervasive Developmental Disorders, Sleep
DNA Methylation of the Oxytocin Receptor across Neurodevelopmental Disorders
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Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Inpatient Psychiatric Treatment of Serious Behavioral Problems in Children with Autism Spectrum Disorder (ASD): Specialized versus General Inpatient Units
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Taylor, Briana J.; Sanders, Kevin B.; Kyle, Marie; Pedersen, Kahsi A.; Veenstra-Vanderweele, Jeremy; Siegel, Matthew – Journal of Autism and Developmental Disorders, 2019
Psychiatric hospitalization of children with autism spectrum disorder (ASD) is common, but there is little comparative information available on different psychiatric hospital treatment models. Children with ASD ages 4-20 were enrolled upon admission to either a specialized (N = 53) or a general child psychiatric unit (N = 27). Caregivers completed…
Descriptors: Psychiatric Hospitals, Patients, Children, Adolescents
Behavioral Symptoms of Reported Abuse in Children and Adolescents with Autism Spectrum Disorder in Inpatient Settings
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Brenner, Jamie; Pan, Zhaoxing; Mazefsky, Carla; Smith, Kahsi A.; Gabriels, Robin – Journal of Autism and Developmental Disorders, 2018
The objective of this study was to examine how behavioral manifestations of trauma due to abuse are expressed in youth with autism spectrum disorder (ASD). Analysis of covariance (ANCOVA) compared outcomes between patients with a caregiver reported history of abuse and those without. Findings indicate that patients with ASD and reported abuse…
Descriptors: Behavior Problems, Trauma, Child Abuse, Autism
Problem Behaviors in Autism Spectrum Disorder: Association with Verbal Ability and Adapting/Coping Skills
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Williams, Diane L.; Siegel, Matthew; Mazefsky, Carla A. – Journal of Autism and Developmental Disorders, 2018
Data from the Autism Inpatient Collection was used to examine the relationship between problem behaviors and verbal ability, which have generally, though not universally, been highly associated. In a comparison of 169 minimally-verbal and 177 fluently-verbal 4 to 20-year-old psychiatric inpatients with ASD, the severity of self-injurious behavior,…
Descriptors: Behavior Problems, Autism, Pervasive Developmental Disorders, Patients
Sleep Problems and Their Relationship to Maladaptive Behavior Severity in Psychiatrically Hospitalized Children with Autism Spectrum Disorder (ASD)
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Sannar, Elise M.; Palka, Tamara; Beresford, Carol; Peura, Christine; Kaplan, Desmond; Verdi, Mary; Siegel, Matthew; Kaplan, Shir; Grados, Marco – Journal of Autism and Developmental Disorders, 2018
We examined the relationship between sleep duration and awakenings to Aberrant Behavior Checklist-Community (ABC-C) and Autism Diagnostic Observation Schedule (ADOS-2) scores in hospitalized youth with ASD and behavioral disturbance. Participants included 106 patients with a stay of at least 10 nights. Sleep in the hospital was recorded by staff…
Descriptors: Sleep, Correlation, Behavior Problems, Severity (of Disability)
The Severe End of the Spectrum: Insights and Opportunities from the Autism Inpatient Collection (AIC)
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Siegel, Matthew – Journal of Autism and Developmental Disorders, 2018
Research on individuals severely affected by autism, including those who are minimally verbal, have intellectual disability or challenging behaviors, has become less common. The Autism Inpatient Collection (AIC) was initiated so data on this group is available to the research community. Ten studies utilizing phenotypic data from the first 350 AIC…
Descriptors: Autism, Patients, Institutionalized Persons, Data Collection
Brief Report: Understanding Crisis Behaviors in Hospitalized Psychiatric Patients with Autism Spectrum Disorder--Iceberg Assessment Interview
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Stark, Kate H.; Barnes, Julia C.; Young, Nicholas D.; Gabriels, Robin L. – Journal of Autism and Developmental Disorders, 2015
Children and adolescents with autism spectrum disorder (ASD) are at risk for emotional dysregulation and behavior problems that can escalate to levels requiring psychiatric hospitalization. Evaluating the etiology of such behaviors can be challenging for health care providers, as individuals with ASD can have difficulty self-reporting concerns.…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Adolescents
The Autism Mental Status Exam: Sensitivity and Specificity Using DSM-5 Criteria for Autism Spectrum Disorder in Verbally Fluent Adults
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Grodberg, David; Weinger, Paige M.; Halpern, Danielle; Parides, Michael; Kolevzon, Alexander; Buxbaum, Joseph D. – Journal of Autism and Developmental Disorders, 2014
The phenotypic heterogeneity of adults suspected of autism spectrum disorder (ASD) requires a standardized diagnostic approach that is feasible in all clinical settings. The autism mental status exam (AMSE) is an eight-item observational assessment that structures the observation and documentation of social, communicative and behavioral signs and…
Descriptors: Pervasive Developmental Disorders, Autism, Adults, Verbal Ability