A 14-year-old with mild mental retardation and behavioral features suggestive of Asperger's syndrome is described. At the onset of puberty lethargic episodes took on a more dramatic form and became more reminiscent of cycloid/manic-depressive psychosis. Neurobiological links with and differences from the syndrome of infantile autism were found.…

This paper presents a case report of a young adult Japanese male with infantile autism who also met diagnostic criteria for seasonal affective disorder and trichotillomania (compulsive hair pulling). The case report deals with difficulties in diagnosing mood disorder in such individuals, potential treatment effectiveness of valproic acid, and…