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Direct linkZhang, Wanqing; Eshghi, Marziye – Journal of Autism and Developmental Disorders, 2019
Regional differences in ASD inpatient care remain understudied. We used the Nationwide Inpatient Sample to examine contributory causes and potential determinants associated with regional variations in ASD hospitalizations. We performed univariate and multivariate analyses to identify differences in ASD hospitalizations across four U.S. Census…
Descriptors: Hospitals, Pervasive Developmental Disorders, Autism, Census Figures
Boada, L.; Lahera, G.; Pina-Camacho, L.; Merchán-Naranjo, J.; Díaz-Caneja, C. M.; Bellón, J. M.; Ruiz-Vargas, J. M.; Parellada, M. – Journal of Autism and Developmental Disorders, 2020
Social cognition impairment is a core shared phenotype in both schizophrenia spectrum disorders (SSD) and autism spectrum disorders (ASD). This study compares social cognition performance through four different instruments in a sample of 147 individuals with ASD or SSD and in healthy controls. We found that both clinical groups perform similarly…
Descriptors: Social Cognition, Autism, Pervasive Developmental Disorders, Comparative Analysis
Siu, Michelle T.; Goodman, Sarah J.; Yellan, Isaac; Butcher, Darci T.; Jangjoo, Maryam; Grafodatskaya, Daria; Rajendram, Rageen; Lou, Youliang; Zhang, Rujun; Zhao, Chunhua; Nicolson, Rob; Georgiades, Stelios; Szatmari, Peter; Scherer, Stephen W.; Roberts, Wendy; Anagnostou, Evdokia; Weksberg, Rosanna – Journal of Autism and Developmental Disorders, 2021
Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, "OXTR," in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD)…
Descriptors: Genetics, Autism, Pervasive Developmental Disorders, Biochemistry
Abulebda, Kamal; Louer, Ryan; Lutfi, Riad; Ahmed, Sheikh Sohail – Journal of Autism and Developmental Disorders, 2018
Children with autism and autism spectrum disorders have a high incidence of neurologic comorbidities. Consequently, evaluation with magnetic resonance imaging (MRI) is deemed necessary. Sedating these patients poses several challenges. This retrospective study compared the efficacy and safety of dexmedetomidine to propofol in sedating autistic…
Descriptors: Diagnostic Tests, Brain Hemisphere Functions, Comorbidity, Patients
Heijnen-Kohl, S. M. J.; Kok, R. M.; Wilting, R. M. H. J.; Rossi, G.; van Alphen, S. S. J. – Journal of Autism and Developmental Disorders, 2017
Autism spectrum disorders (ASD) are difficult to detect in old age. This study examined if ASD symptoms in older adults (age > 60) can be detected with the Dutch informant personality questionnaire, (Hetero-Anamnestische Persoonlijkheidsvragenlijst, HAP) in a mental health setting. Patients with ASD (N = 40) were compared to patients with a…
Descriptors: Screening Tests, Pervasive Developmental Disorders, Autism, Psychiatry
Booules-Katri, Tereza-Maria; Pedreño, Carla; Navarro, Jose-Blás; Pamias, Montserrat; Obiols, Jordi E. – Journal of Autism and Developmental Disorders, 2019
The similarities between high functioning autism (HFA) and schizotypal-schizoid personality disorder (SSPD) in terms of social cognition and interpersonal deficits may lead to confusion in symptom interpretation, and consequently result in misdiagnosis. Thus, this study aims to investigate differences in mentalizing with particular interest on the…
Descriptors: Theory of Mind, Autism, Pervasive Developmental Disorders, Schizophrenia
Krüger, Britta; Kaletsch, Morten; Pilgramm, Sebastian; Schwippert, Sven-Sören; Hennig, Jürgen; Stark, Rudolf; Lis, Stefanie; Gallhofer, Bernd; Sammer, Gebhard; Zentgraf, Karen; Munzert, Jörn – Journal of Autism and Developmental Disorders, 2018
One major characteristic of autism spectrum disorder (ASD) is problems with social interaction and communication. The present study explored ASD-related alterations in perceiving emotions expressed via body movements. 16 participants with ASD and 16 healthy controls observed video scenes of human interactions conveyed by point-light displays. They…
Descriptors: Autism, Pervasive Developmental Disorders, Emotional Response, Nonverbal Communication
Kuriakose, Sarah; Filton, Beryl; Marr, Mollie; Okparaeke, Eugene; Cervantes, Paige; Siegel, Matthew; Horwitz, Sarah; Havens, Jennifer – Journal of Autism and Developmental Disorders, 2018
Youth with autism spectrum disorder (ASD) are psychiatrically hospitalized at high rates. Though specialized psychiatric units are effective, few specialized units exist. The ASD Care Pathway (ASD-CP) was developed as a scalable approach to improving care in general psychiatric units through staff training and a package of autism-specific…
Descriptors: Children, Adolescents, Youth, Psychiatric Hospitals
Danzer, Enrico; Hoffman, Casey; D'Agostino, Jo Ann; Miller, Judith S.; Waqar, Lindsay N.; Gerdes, Marsha; Bernbaum, Judy C.; Rosenthal, Hannah; Rintoul, Natalie E.; Herkert, Lisa M.; Peranteau, William H.; Flake, Alan W.; Adzick, N. Scott; Hedrick, Holly L. – Journal of Autism and Developmental Disorders, 2018
To determine the rate and predictors of autism spectrum disorder (ASD) in congenital diaphragmatic hernia (CDH). Between 06/2004 and 09/2015 a total of 110 CDH survivors underwent neurodevelopmental (ND) testing and screening for ASD, followed by a full autism diagnostic evaluation if indicated at our institution. We found a 9 time higher rate of…
Descriptors: Risk, Statistical Analysis, Incidence, Patients
Ozgen, H.; Hellemann, G. S.; de Jonge, M. V.; Beemer, F. A.; van Engeland, H. – Journal of Autism and Developmental Disorders, 2013
We investigated the predictive power of morphological features in 224 autistic patients and 224 matched-pairs controls. To assess the relationship between the morphological features and autism, we used the receiver operator curves (ROC). In addition, we used recursive partitioning (RP) to determine a specific pattern of abnormalities that is…
Descriptors: Autism, Patients, Comparative Analysis, Predictor Variables
Wong, Virginia C. N.; Fung, Cecilia K. Y.; Wong, Polly T. Y. – Journal of Autism and Developmental Disorders, 2014
Data from 1,261 Chinese Autistic Spectrum Disorder (ASD) patients were evaluated and categorized into dysmorphic (10.79%) and non-dysmorphic groups (89.21%) upon physical examination by the presence of dysmorphic features. Abnormal MRI/CT result, IQ scores and epilepsy were significantly associated with the dysmorphic group of ASD children.…
Descriptors: Foreign Countries, Pervasive Developmental Disorders, Autism, Classification
Pagani, Marco; Manouilenko, Irina; Stone-Elander, Sharon; Odh, Richard; Salmaso, Dario; Hatherly, Robert; Brolin, Fredrik; Jacobsson, Hans; Larsson, Stig A.; Bejerot, Susanne – Journal of Autism and Developmental Disorders, 2012
Specific biological markers for Autism Spectrum Disorder (ASD) have not yet been established. Functional studies have shown abnormalities in the anatomo-functional connectivity of the limbic-striatal "social" brain. This study aimed to investigate regional cerebral blood flow (rCBF) at rest. Thirteen patients with ASD of normal intelligence and…
Descriptors: Metabolism, Autism, Intelligence Quotient, Patients
Grodberg, David; Weinger, Paige M.; Halpern, Danielle; Parides, Michael; Kolevzon, Alexander; Buxbaum, Joseph D. – Journal of Autism and Developmental Disorders, 2014
The phenotypic heterogeneity of adults suspected of autism spectrum disorder (ASD) requires a standardized diagnostic approach that is feasible in all clinical settings. The autism mental status exam (AMSE) is an eight-item observational assessment that structures the observation and documentation of social, communicative and behavioral signs and…
Descriptors: Pervasive Developmental Disorders, Autism, Adults, Verbal Ability
Hippler, Kathrin; Viding, Essi; Klicpera, Christian; Happe, Francesca – Journal of Autism and Developmental Disorders, 2010
Hans Asperger originally used the term "autistic psychopathy" to describe his patients on the autism spectrum, leading to a possible confusion with psychopathic disorder and delinquent behaviour. We conducted a penal register search for 177 former patients of Asperger's clinic with a childhood diagnosis of "autistic…
Descriptors: Autism, Asperger Syndrome, Patients, Foreign Countries
Uchiyama, Tokio; Kurosawa, Michiko; Inaba, Yutaka – Journal of Autism and Developmental Disorders, 2007
It has been suggested that the measles, mumps, and rubella vaccine (MMR) is a cause of regressive autism. As MMR was used in Japan only between 1989 and 1993, this time period affords a natural experiment to examine this hypothesis. Data on 904 patients with autism spectrum disorders (ASD) were analyzed. During the period of MMR usage no…
Descriptors: Foreign Countries, Patients, Incidence, Autism
