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Cerebro-Cerebellar Functional Connectivity Is Associated with Cerebellar Excitation-Inhibition Balance in Autism Spectrum Disorder
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Hegarty, John P., II; Weber, Dylan J.; Cirstea, Carmen M.; Beversdorf, David Q. – Journal of Autism and Developmental Disorders, 2018
Atypical functional connectivity (FC) and an imbalance of excitation-to-inhibition (E/I) have been previously reported in cerebro-cerebellar circuits in autism spectrum disorder (ASD). The current investigation used resting state fMRI and proton magnetic resonance spectroscopy ([superscript 1]H-MRS) to examine the relationships between E/I…
Descriptors: Brain Hemisphere Functions, Diagnostic Tests, Autism, Pervasive Developmental Disorders
Brief Report: Approaches to [Superscript 31]P-MRS in Awake, Non-Sedated Children with and without Autism Spectrum Disorder
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Erickson, Laura C.; Scott-Van Zeeland, Ashley A.; Hamilton, Gavin; Lincoln, Alan; Golomb, Beatrice A. – Journal of Autism and Developmental Disorders, 2012
We piloted a suite of approaches aimed to facilitate a successful series of up to four brain and muscle [superscript 31]Phosphorus-Magnetic Resonance Spectroscopy ([superscript 31]P-MRS) scans performed in one session in 12 "awake", non-sedated subjects (ages 6-18), 6 with autism spectrum disorders (ASD) and 6 controls. We targeted advanced…
Descriptors: Autism, Brain, Pervasive Developmental Disorders, Spectroscopy