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Direct linkHegarty, John P., II; Weber, Dylan J.; Cirstea, Carmen M.; Beversdorf, David Q. – Journal of Autism and Developmental Disorders, 2018
Atypical functional connectivity (FC) and an imbalance of excitation-to-inhibition (E/I) have been previously reported in cerebro-cerebellar circuits in autism spectrum disorder (ASD). The current investigation used resting state fMRI and proton magnetic resonance spectroscopy ([superscript 1]H-MRS) to examine the relationships between E/I…
Descriptors: Brain Hemisphere Functions, Diagnostic Tests, Autism, Pervasive Developmental Disorders
Abdullah, Maryam M.; Ly, Agnes R.; Goldberg, Wendy A.; Clarke-Stewart, K. Alison; Dudgeon, John V.; Mull, Christopher G.; Chan, Tony J.; Kent, Erin E.; Mason, Andrew Z.; Ericson, Jonathon E. – Journal of Autism and Developmental Disorders, 2012
To examine possible links between neurotoxicant exposure and neuropsychological disorders and child behavior, relative concentrations of lead, mercury, and manganese were examined in prenatal and postnatal enamel regions of deciduous teeth from children with Autism Spectrum Disorders (ASDs), high levels of disruptive behavior (HDB), and typically…
Descriptors: Autism, Child Behavior, Metallurgy, Hazardous Materials
Kleinhans, Natalia M.; Richards, Todd; Weaver, Kurt E.; Liang, Olivia; Dawson, Geraldine; Aylward, Elizabeth – Journal of Autism and Developmental Disorders, 2009
Amygdala dysfunction has been proposed as a critical contributor to social impairment in autism spectrum disorders (ASD). The current study investigated biochemical abnormalities in the amygdala in 20 high functioning adults with autistic disorder or Asperger's disorder and 19 typically developing adults matched on age and IQ. Magnetic resonance…
Descriptors: Autism, Asperger Syndrome, Brain, Adults
