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Dager, Stephen R.; Corrigan, Neva M.; Estes, Annette; Shaw, Dennis W. W. – Journal of Autism and Developmental Disorders, 2012
The authors respond to a recent letter (Rossignol and Frye 2011) critical of their paper, "Proton magnetic resonance spectroscopy and MRI reveal no evidence for brain mitochondrial dysfunction in children with autism spectrum disorder" (Corrigan et al. 2011). Further considerations regarding the assessment of mitochondrial dysfunction in autism…
Descriptors: Evidence, Autism, Genetics, Pervasive Developmental Disorders
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Corrigan, Neva M.; Shaw, Dennis. W. W.; Richards, Todd L.; Estes, Annette M.; Friedman, Seth D.; Petropoulos, Helen; Artru, Alan A.; Dager, Stephen R. – Journal of Autism and Developmental Disorders, 2012
Brain mitochondrial dysfunction has been proposed as an etiologic factor in autism spectrum disorder (ASD). Proton magnetic resonance spectroscopic imaging ([superscript 1]HMRS) and MRI were used to assess for evidence of brain mitochondrial dysfunction in longitudinal samples of children with ASD or developmental delay (DD), and cross-sectionally…
Descriptors: Evidence, Autism, Etiology, Brain Hemisphere Functions