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A Review of Cardiac Autonomic Measures: Considerations for Examination of Physiological Response in Children with Autism Spectrum Disorder
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Benevides, Teal W.; Lane, Shelly J. – Journal of Autism and Developmental Disorders, 2015
The autonomic nervous system (ANS) is responsible for multiple physiological responses, and dysfunction of this system is often hypothesized as contributing to cognitive, affective, and behavioral responses in children. Research suggests that examination of ANS activity may provide insight into behavioral dysregulation in children with autism…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Physiology
Beyond Modularisation: The Need of a Socio-Neuro-Constructionist Model of Autism
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López, Beatriz – Journal of Autism and Developmental Disorders, 2015
Autism is a "developmental" disorder defined by "social and communication" impairments. Current theoretical approaches and research studies however conceptualise autism as both static and independent from the social context in which it develops. Two lines of research stand out from this general trend. First, research from the…
Descriptors: Autism, Developmental Disabilities, Symptoms (Individual Disorders), Research
Brief Report: Pathophysiology of Autism: Neurochemistry.
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Cook, Edwin H., Jr. – Journal of Autism and Developmental Disorders, 1996
This paper reviews what is known about the role of neurochemicals in controlling the development of the brain and in the pathophysiology of autism. Suggested approaches to further research involve using animal models, examining effects of drugs on neurochemicals, and using such technologies as positron emission tomography and magnetic resonance…
Descriptors: Autism, Biochemistry, Chemistry, Etiology
Motor Signs Distinguish Children with High Functioning Autism and Asperger's Syndrome from Controls
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Jansiewicz, Eva M.; Goldberg, Melissa C.; Newschaffer, Craig J.; Denckla, Martha B.; Landa, Rebecca; Mostofsky, Stewart H. – Journal of Autism and Developmental Disorders, 2006
While many studies of motor control in autism have focused on specific motor signs, there has been a lack of research examining the complete range of subtle neuromotor signs. This study compared performance on a neurologic examination standardized for children (PANESS, Physical and Neurological Exam for Subtle Signs, Denckla ["1974 Developmental…
Descriptors: Children, Autism, Asperger Syndrome, Psychomotor Skills
A New Neurobehavioral Model of Autism in Mice: Pre-and Postnatal Exposure to Sodium Valproate
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Wagner, George C.; Reuhl, Kenneth R.; Cheh, Michelle; McRae, Paulette; Halladay, Alycia K. – Journal of Autism and Developmental Disorders, 2006
Autism symptoms, including impairments in language development, social interactions, and motor skills, have been difficult to model in rodents. Since children exposed in utero to sodium valproate (VPA) demonstrate behavioral and neuroanatomical abnormalities similar to those seen in autism, the neurodevelopmental effects of this antiepileptic…
Descriptors: Language Acquisition, Autism, Animals, Self Destructive Behavior
Brief Report: Medial Temporal Lobe and Autism: A Putative Animal Model in Primates.
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Bachevalier, Jocelyne – Journal of Autism and Developmental Disorders, 1996
Research on humans and monkeys is reviewed that supports the view that the medial temporal lobe, and, perhaps more specifically the amygdala, is the neural substrate underlying social deficits in autism. The relationship of early medial temporal lobe lesions to memory and socioemotional behavior is reviewed, as are the roles of the amygdala and…
Descriptors: Autism, Emotional Development, Etiology, Interpersonal Competence