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Wink, Logan K.; Reisinger, Debra L.; Horn, Paul; Shaffer, Rebecca C.; O'Brien, Kaela; Schmitt, Lauren; Dominick, Kelli R.; Pedapati, Ernest V.; Erickson, Craig A. – Journal of Autism and Developmental Disorders, 2021
Dysregulation of glutamate neurotransmission plays a critical role in autism spectrum disorder (ASD) pathophysiology and is a primary target for core deficit research treatment trials. The mechanism of action of ketamine has striking overlap with the theory of ASD as a disorder of synaptic communication and neuronal networks. This two-dose,…
Descriptors: Autism, Pervasive Developmental Disorders, Neurology, Adolescents
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Morton, Hannah E.; Gillis, Jennifer M.; Zale, Emily L.; Brimhall, Kim C.; Romanczyk, Raymond G. – Journal of Autism and Developmental Disorders, 2022
Bullying victimization is a prevalent concern for neurodivergent (e.g., autistic, ADHD) youth. Bullying assessment methods vary widely and there is currently no questionnaire specific to neurodivergent youth. The "Assessment of Bullying Experiences" ("ABE") was created to fill this gap. The "ABE" questionnaire was…
Descriptors: Bullying, Evaluation, Parents, Youth
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Mercado, Eduardo, III; Church, Barbara A. – Journal of Autism and Developmental Disorders, 2016
Children with autism spectrum disorder (ASD) sometimes have difficulties learning categories. Past computational work suggests that such deficits may result from atypical representations in cortical maps. Here we use neural networks to show that idiosyncratic transformations of inputs can result in the formation of feature maps that impair…
Descriptors: Autism, Pervasive Developmental Disorders, Brain Hemisphere Functions, Neurology
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Karten, Ariel; Hirsch, Joy – Journal of Autism and Developmental Disorders, 2015
Neural mechanisms that underlie language disability in autism spectrum disorder (ASD) have been associated with reduced excitatory processes observed as positive blood oxygen level dependent (BOLD) responses. However, negative BOLD responses (NBR) associated with language and inhibitory processes have been less studied in ASD. In this study,…
Descriptors: Autism, Pervasive Developmental Disorders, Receptive Language, Language Impairments
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Wong, Virginia; Wong, Sik Nin – Journal of Autism and Developmental Disorders, 1991
Brainstem auditory evoked potentials were compared in 109 children with infantile autism, 38 with autistic condition, 19 with mental retardation, and 20 normal children. Children with infantile autism or autistic condition had significantly longer brainstem transmission time than normal children suggesting neurological damage as the basis of…
Descriptors: Autism, Children, Etiology, Neurological Impairments