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McPartland, James C.; Lerner, Matthew D.; Bhat, Anjana; Clarkson, Tessa; Jack, Allison; Koohsari, Sheida; Matuskey, David; McQuaid, Goldie A.; Su, Wan-Chun; Trevisan, Dominic A. – Journal of Autism and Developmental Disorders, 2021
During the last 40 years, neuroscience has become one of the most central and most productive approaches to investigating autism. In this commentary, we assemble a group of established investigators and trainees to review key advances and anticipated developments in neuroscience research across five modalities most commonly employed in autism…
Descriptors: Autism, Pervasive Developmental Disorders, Neurosciences, Research
Edwards, Laura A.; Wagner, Jennifer B.; Tager-Flusberg, Helen; Nelson, Charles A. – Journal of Autism and Developmental Disorders, 2017
In this study, we investigated neural precursors of language acquisition as potential endophenotypes of autism spectrum disorder (ASD) in 3-month-old infants at high and low familial ASD risk. Infants were imaged using functional near-infrared spectroscopy while they listened to auditory stimuli containing syllable repetitions; their neural…
Descriptors: Autism, Pervasive Developmental Disorders, Spectroscopy, Infants
Harada, Masafumi; Taki, Masako M.; Nose, Ayumi; Kubo, Hitoshi; Mori, Kenji; Nishitani, Hiromu; Matsuda, Tsuyoshi – Journal of Autism and Developmental Disorders, 2011
Amino acids related to neurotransmitters and the GABAergic/glutamatergic system were measured using a 3 T-MRI instrument in 12 patients with autism and 10 normal controls. All measurements were performed in the frontal lobe (FL) and lenticular nuclei (LN) using a conventional sequence for n-acetyl aspartate (NAA) and glutamate (Glu), and the…
Descriptors: Autism, Spectroscopy, Brain, Neurological Organization