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Yukihiko Shirayama; Kazuki Matsumoto; Fumio Osone; Akira Hara; Siqing Guan; Sayo Hamatani; Katsumasa Muneoka; Koichi Sato; Akihiro Okada; Tokuzou Yokokawa – Journal of Autism and Developmental Disorders, 2024
Proton magnetic resonance spectroscopy ([superscript 1]H-MRS) has shown inconsistent alterations in brain metabolites of adults with autism spectrum disorder (ASD). We investigated brain metabolites in the medial prefrontal cortex and amygdala of 24 drug-naive adults with ASD and no intellectual disability and 24 non-ASD control subjects, using…
Descriptors: Brain, Brain Hemisphere Functions, Adults, Autism Spectrum Disorders
Carré, Arnaud; Chevallier, Coralie; Robel, Laurence; Barry, Caroline; Maria, Anne-Solène; Pouga, Lydia; Philippe, Anne; Pinabel, François; Berthoz, Sylvie – Journal of Autism and Developmental Disorders, 2015
Abnormal functioning of primary brain systems that express and modulate basic emotional drives are increasingly considered to underlie mental disorders including autism spectrum disorders. We hypothesized that ASD are characterized by disruptions in the primary systems involved in the motivation for social bonding. Twenty adults with ASD were…
Descriptors: Brain Hemisphere Functions, Comparative Analysis, Autism, Pervasive Developmental Disorders