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McDougle, Christopher J.; Kresch, Laura E.; Posey, David J. – Journal of Autism and Developmental Disorders, 2000
Results from two studies indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in children with autism. A study of the selective SRI fluvoxamine found it to be significantly better than placebo for reducing repetitive…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children

Gordon, C. T. – Journal of Autism and Developmental Disorders, 2000
This commentary discusses study results that indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in treating repetitive or ritualized behaviors in children with autism. The need for concurrent genetic and biochemical…
Descriptors: Adults, Behavior Disorders, Behavior Problems, Children

King, Bryan H. – Journal of Autism and Developmental Disorders, 2000
This article reviews the psychopharmacological treatment of aggression, mood disturbances, and self-injurious behavior in persons with autistic disorder. It highlights the use of dopaminergic drugs, serotonergic drugs, opioidergic drugs, adrenergic drugs, thymoleptic drugs, and glutamatergic drugs for their potential utility in treating…
Descriptors: Adults, Aggression, Behavior Disorders, Behavior Problems