This article describes several features important in the success of using a behavioral model when treating individuals with autism and presents remaining issues to be addressed for improving treatment effectiveness. It urges future research to include strict empirical designs that allow for sound inferences regarding the parameters of treatment…

This commentary discusses the wide acceptance of and the expenditure of limited resources on unproven behavioral therapies for individuals with autism. Considerations that need to be reviewed before adopting a behavioral treatment are outlined, including the need to establish whether direct effects can be attributed to a treatment. (Contains 11…

This commentary discusses the use of pharmacological treatments to reduce over activity and hyperactivity in children with autism. While it concedes that some medications, particularly antipsychotics, can effectively reduce over activity, it cautions that the effects of psychotropic medications on inattention remain poorly defined and stresses the…

This paper reviews findings from comprehensive early intervention studies with young children with autism and formulates questions that need to be answered to establish efficacious, accessible early treatment. Results suggest that intensive, very early treatment appears to lessen the debilitating effects of autism. Research questions involve…

This commentary discusses study results that indicate the nonselective serotonin reuptake inhibitor (SRI) clomipramine is more efficacious than the relatively selective norepinephrine reuptake inhibitor desipramine and placebo in treating repetitive or ritualized behaviors in children with autism. The need for concurrent genetic and biochemical…