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Autism Spectrum Disorder in an Unselected Cohort of Children with Neurofibromatosis Type 1 (NF1)
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Eijk, S.; Mous, S. E.; Dieleman, G. C.; Dierckx, B.; Rietman, A. B.; de Nijs, P. F. A.; ten Hoopen, L. W.; van Minkelen, R.; Elgersma, Y.; Catsman-Berrevoets, C. E.; Oostenbrink, R.; Legerstee, J. S. – Journal of Autism and Developmental Disorders, 2018
In a non-selected sample of children with Neurofibromatosis type 1 (NF1) the prevalence rate of autism spectrum disorder (ASD) and predictive value of an observational (ADOS)--and questionnaire-based screening instrument were assessed. Complete data was available for 128 children. The prevalence rate for clinical ASD was 10.9%, which is clearly…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Neurological Impairments
Prediction of Autism at 3 Years from Behavioural and Developmental Measures in High-Risk Infants: A Longitudinal Cross-Domain Classifier Analysis
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Bussu, G.; Jones, E. J. H.; Charman, T.; Johnson, M. H.; Buitelaar, J. K.; Baron-Cohen, S.; Bedford, R.; Bolton, P.; Blasi, A.; Chandler, S.; Cheung, C.; Davies, K.; Elsabbagh, M.; Fernandes, J.; Gammer, I.; Garwood, H.; Gliga, T.; Guiraud, J.; Hudry, K.; Liew, M.; Lloyd-Fox, S.; Maris, H.; O'Hara, L.; Pasco, G.; Pickles, A.; Ribeiro, H.; Salomone, E.; Tucker, L.; Volein, A. – Journal of Autism and Developmental Disorders, 2018
We integrated multiple behavioural and developmental measures from multiple time-points using machine learning to improve early prediction of individual Autism Spectrum Disorder (ASD) outcome. We examined Mullen Scales of Early Learning, Vineland Adaptive Behavior Scales, and early ASD symptoms between 8 and 36 months in high-risk siblings (HR; n…
Descriptors: Prediction, Autism, Symptoms (Individual Disorders), Classification
Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder
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Dimian, Adele F.; Botteron, Kelly N.; Dager, Stephen R.; Elison, Jed T.; Estes, Annette M.; Pruett, John R., Jr.; Schultz, Robert T.; Zwaigenbaum, Lonnie; Piven, Joseph; Wolff, Jason J. – Journal of Autism and Developmental Disorders, 2017
Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose…
Descriptors: Risk, Self Destructive Behavior, Autism, Pervasive Developmental Disorders