Rett syndrome is a severe neurodevelopmental disorder that affects about 1 in 10,000 females. Clinical trials of disease modifying therapies are on the rise, but there are few psychometrically sound caregiver-reported outcome measures available to assess treatment benefit. We report on a new caregiver-reported outcome measure, the Rett Caregiver…

In recent years, there has been a proliferation of instruments for assessing mental health (MH) among autistic people. This study aimed to review the psychometric properties of broadband instruments used to assess MH problems among autistic people. In accordance with the PRISMA guidelines (PROSPERO: CRD42022316571) we searched the APA PsycINFO via…

There are few evaluated economic tools to assess change in autism. This study examined the inter-rater reliability of the Developmental Disabilities Children's Global Assessment Scale (DD-CGAS), and the OSU Autism Clinical Global Impression (OSU Autism CGI) in a European setting. Using these scales, 16 clinicians with multidisciplinary…

The Autism Mental Status Examination (AMSE) described here is an eight-item observational assessment that prompts the observation and recording of signs and symptoms of autism spectrum disorders (ASD). The AMSE is intended to take place seamlessly in the context of a clinical exam and produces a total score. Subjects were independently…

The Prudhoe Cognitive Function Test (PCFT) directly measures the cognitive abilities of people with intellectual impairment. This study examined the relationship between this instrument and the Kaufman Brief Intelligence Test (K-BIT) and two shorter versions of the same scale. High correlations between the verbal and performance sections of the…

Recent insight into the underlying molecular and cellular mechanisms of fragile X syndrome (FXS) has led to the proposal and development of new pharmaceutical treatment strategies, and the initiation of clinical trials aimed at correcting core symptoms of the developmental disorder. Consequently, there is an urgent and critical need for outcome…

The PEP-R (psychoeducational profile revised) is an instrument that has been used in many countries to assess abilities and formulate treatment programs for children with autism and related developmental disorders. To the end to provide further information on the PEP-R's psychometric properties, a large sample (N = 137) of children presenting…

To date, no standardized measures have been developed to evaluate the mealtime behavior of children with autism. The Brief Autism Mealtime Behavior Inventory (BAMBI) was designed to measure mealtime behavior problems observed in children with autism. Caregivers of 40 typically developing children and 68 children with autism completed the BAMBI,…

The reliable diagnosis of Autism/Autism Spectrum Disorder in pre-school children is important for access to early intervention and for accurate ascertainment for research. This paper explores the combined use of two standardised assessment instruments--the Autism Diagnostic Interview Revised (ADI-R) and the Autism Diagnostic Observation Schedule…

The ability to identify children who require specialist assessment for the possibility of autism at as early an age as possible has become a growing area of research. A number of measures have been developed as potential screening tools for autism. The reliability and validity of one of these measures for screening for autism in young children…

This paper reviews the psychometric properties, treatment utility, and conceptual basis of instruments used to identify the functions of aberrant behaviors in people with developmental disabilities. Instruments include the Motivational Assessment Scale, Motivation Analysis Rating Scale, Functional Analysis Interview Form, and Functional Analysis…

Psychometric data are presented for 223 children and adults with autism, pervasive developmental disorder not otherwise specified (PDDNOS), or nonspectrum diagnoses who took the Autism Diagnostic Observation Schedule-Generic. Within each module, diagnostic groups were equivalent on expressive language levels. Results indicate substantial…

A study of 10 children (ages 3-6) with pervasive developmental disorders investigated the interrater reliability of the Psychoeducational Profile (PEP). Results show good interrater reliability for the developmental items, indicating that the PEP can be used to evaluate progress in development of children with pervasive developmental disorders.…

A study of 319 individuals with autism (ages 3-43) and 113 other subjects found that a single set of criteria, as operationalized by individually structured questions in the Autism Diagnostic Interview and Autism Diagnostic Interview-Revised, was effective in differentiating autism from mental disabilities and language impairment. (Author/CR)

Four staff members completed 3 questionnaires evaluating quantitative and qualitative aspects of compulsive and autistic behaviors of 17 young autistic adults in a farmstead residential facility. Results affirmed the utility and applicability of obsessive-compulsive assessment devices in evaluating behavior of autistic adults. (Author/DB)