The Helping Early Literacy with Practice Strategies (HELPS) Program was developed by integrating 8 evidence-based fluency-building instructional strategies into a structured program that can be feasibly implemented by educators. The HELPS Program has been shown in previous research to significantly improve elementary-aged students' reading abilities, but the effects of HELPS have not been evaluated with an important and increasing sub-population of U.S. students, English language learners (ELLs). As such, the purpose of this control group comparison study was to evaluate HELPS with Latino ELLs. Findings showed that ELLs who received HELPS scored significantly higher than the control group on standardized measures of fluency and comprehension. Although this study represents an initial attempt to understand the effects of HELPS with ELLs, the findings have implications for educators and researchers who work with ELLs.