Acid-base titration concepts and experiments are ubiquitous, yet challenging, aspects of the general chemistry curriculum. Most general chemistry courses include at least one acid-base titration laboratory experiment, though the focus is often on determining the concentration, pK[subscript a], or molar mass of an analyte rather than on the details…

A practical focusing on the synthesis, isolation, and hydrolysis of ammonia borane (AB), H[subscript 3]N·BH[subscript 3], was developed for first-year undergraduate students. By requiring students to propose their own experimental setup to measure the amount of gas produced upon hydrolysis, experimental design skills were introduced and developed…

Experimental design is a desirable outcome of laboratory education. Incorporating inquiry into the laboratory curriculum is attractive, but there are acknowledged concerns from practical, theoretical, and epistemological perspectives, and these are accentuated in upper-division courses. In this work, we draw on the extensive literature relating to…

The design and implementation of an advanced guided-inquiry experiment for the organic laboratory is described. Grubbs's second-generation catalyst is used to effect the ring-closing metathesis of diethyl diallylmalonate. The reaction is carried out under an inert atmosphere at room temperature and monitored by argentic TLC. The crude reaction is…

This project is conducted by students during the second semester of their second year in our educational institution. This project constitutes an initiation into research and allows a broadening of knowledge, a development in autonomy, organization, team work, and initiative. It helps prepare the student-engineer for an internship in industry. The…

The study describes how to design and optimize an experiment with multiple factors and multiple responses. The experiment uses fractional factorial analysis as a screening experiment only to identify important instrumental factors and does not use response surface methodology to find the optimal set of conditions.