The utilization of modeling tools has gained significant attention recently. These models typically involve a series of partial differential equations, which can be challenging for novice modelers. This paper presented an approach in practical teaching of modeling tools for ion-exchange chromatography with three parts: model introduction, model…

The ability to extract structural information from a drawing of a molecule is key to being successful in organic chemistry. One source of difficulty for novices in interpreting structures is that hydrogens bound to carbon are represented implicitly in the often-used line-angle structures. Other representations that explicitly show hydrogens, such…

Synthesis of (Z)-alkenes is challenging because the (E) stereoisomers are usually more stable. Energy transfer photocatalysis has emerged as an efficient strategy for (E) [right arrow] (Z) alkene isomerization. We report the development of an advanced undergraduate laboratory experiment that introduces students to contemporary organic…

A symmetry activity using student-built models was developed in line with faculty-developed pedagogical goals and a collaborative learning framework. The activity took place in a 3-h laboratory portion of an upper-division inorganic chemistry course. It required students to identify symmetry elements for seven molecules using common 2D…

Teaching the three-dimensional structure of saccharides has consistently been a challenging aspect of organic chemistry courses, impeding students' ability to grasp more advanced topics in biochemistry and food chemistry. In this article, we designed and developed a novel d-glucopyranose model using 3D printing technology for the first time. This…

Organic molecules are invisible objects, but they can be visualized and manipulated by using molecular models. The object-based learning (OBL) approach, which is an educational tool developed for museums and collection items, is tailored and applied to a first-year bachelor course of organic chemistry. At the beginning of the course, each student…

The analysis of functional groups in organic compounds and inorganic ions in salts is a laboratory experiment that forms an inevitable part of the undergraduate chemistry curriculum in the science field all over the world. With this experiment, the student learns the testing techniques for the chemicals and gets a true sense of the importance of…

This research aimed to use students' modeling processes as a means of scientific inquiry. Students constructed models to explain the interactions between felodipine R and S and protein. The approach encouraged active student participation in molecular interaction modeling and offered students a "model-based teaching" experience for…

We have developed a guided-inquiry laboratory exercise in which students perform viscosity measurements to infer the structure of poly(vinyl alcohol) (PVA) in aqueous solution. The activity combines both experiments and modeling. In the experimental portion of the exercise, students measure the viscosity of several solutions of PVA with differing…

We surveyed 196 individuals who study or work in STEM regarding the role models and inspirations that had an influence on them pursuing STEM education and careers. The data showed that role models influenced around 30% of the sample. These role models can then be divided into three overarching types, teachers, family, and well-known scientists,…

The acid-catalyzed dehydration of regioisomeric methylcyclohexanols is a classic organic chemistry experiment featured in a variety of laboratory textbooks and literature. The mechanistic details of this reaction have received an inconsistent and occasionally inaccurate treatment, wherein the reaction has been described as a mix of E1, E2-like,…

Effective spatial visualization and reasoning skills are often credited for students' success in science and engineering courses. However, students enrolled in these science courses are not always exposed to or trained properly on the best ways to utilize models to aid in their learning. Improving spatial visualization techniques with 3D models,…

Metamodeling ideas move beyond using a model to solve a problem to consider the nature and purpose of a model, such as reasoning about a model's empirical basis and understanding why and how a model might change or be replaced. Given that chemistry relies heavily on the use of models to describe particulate-level phenomena, developing…

The process of diffusion is intimately related to random molecular displacement and is central to many problems in chemistry. Here, we provide an intuitive derivation of the diffusion equation based on the analysis of the random trajectories of particles generated and plotted by simple MATLAB and Python scripts. The codes are very simple and…

The use of molecular models in chemistry and biochemistry classes is very effective in helping students understand covalent bonds and the chemical structure of molecules. However, conventional molecular models cannot represent intermolecular interactions such as hydrogen bonds and electrostatic interactions. Herein, we describe 3D printed…