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Cognitive and Adaptive Advantages of Growth Hormone Treatment in Children with Prader-Willi Syndrome
Peer reviewed
Direct linkDykens, Elisabeth M.; Roof, Elizabeth; Hunt-Hawkins, Hailee – Journal of Child Psychology and Psychiatry, 2017
Background: People with Prader-Willi syndrome (PWS) typically have mild to moderate intellectual deficits, compulsivity, hyperphagia, obesity, and growth hormone deficiencies. Growth hormone treatment (GHT) in PWS has well-established salutatory effects on linear growth and body composition, yet cognitive benefits of GHT, seen in other patient…
Descriptors: Genetic Disorders, Therapy, Cognitive Ability, Adjustment (to Environment)
McAuley, Tara; Crosbie, Jennifer; Charach, Alice; Schachar, Russell – Journal of Child Psychology and Psychiatry, 2014
Background: Response inhibition, working memory, and response variability are possible endophenotypes of ADHD based on their association with the disorder and evidence of heritability. One of the critical although rarely studied criteria for a valid endophenotype is that it persists despite waxing and waning of the overt manifestations of the…
Descriptors: Attention Deficit Hyperactivity Disorder, Inhibition, Children, Adolescents
Fricke, Silke; Burgoyne, Kelly; Bowyer-Crane, Claudine; Kyriacou, Maria; Zosimidou, Alexandra; Maxwell, Liam; Lervåg, Arne; Snowling, Margaret J.; Hulme, Charles – Journal of Child Psychology and Psychiatry, 2017
Background: Oral language skills are a critical foundation for literacy and more generally for educational success. The current study shows that oral language skills can be improved by providing suitable additional help to children with language difficulties in the early stages of formal education. Methods: We conducted a randomized controlled…
Descriptors: Oral Language, Language Skills, Language Impairments, Randomized Controlled Trials
Snowling, Margaret J.; Duff, Fiona J.; Nash, Hannah M.; Hulme, Charles – Journal of Child Psychology and Psychiatry, 2016
Background: Children with language impairment (LI) show heterogeneity in development. We tracked children from pre-school to middle childhood to characterize three developmental trajectories: resolving, persisting and emerging LI. Methods: We analyzed data from children identified as having preschool LI, or being at family risk of dyslexia,…
Descriptors: Language Impairments, Child Development, Developmental Stages, At Risk Persons
Toplak, Maggie E.; Sorge, Geoff B.; Flora, David B.; Chen, Wai; Banaschewski, Tobias; Buitelaar, Jan; Ebstein, Richard; Eisenberg, Jacques; Franke, Barbara; Gill, Michael; Miranda, Ana; Oades, Robert D.; Roeyers, Herbert; Rothenberger, Aribert; Sergeant, Joseph; Sonuga-Barke, Edmund; Steinhausen, Hans-Christoph; Thompson, Margaret; Tannock, Rosemary; Asherson, Philip; Faraone, Stephen V. – Journal of Child Psychology and Psychiatry, 2012
Objective: To examine the factor structure of attention-deficit/hyperactivity disorder (ADHD) in a clinical sample of 1,373 children and adolescents with ADHD and their 1,772 unselected siblings recruited from different countries across a large age range. Hierarchical and correlated factor analytic models were compared separately in the ADHD and…
Descriptors: Attention Deficit Hyperactivity Disorder, Siblings, Factor Structure, Adolescents
Miller, Meghan; Loya, Fred; Hinshaw, Stephen P. – Journal of Child Psychology and Psychiatry, 2013
Background: We prospectively followed an ethnically and socioeconomically diverse sample of girls with attention-deficit/hyperactivity disorder (ADHD) (n = 140) and a matched comparison sample (n = 88) from childhood through young adulthood to evaluate developmental trajectories of executive functions (EF) and associations between EF trajectories…
Descriptors: Executive Function, Females, Attention Deficit Hyperactivity Disorder, Comparative Analysis
Galler, Janina R.; Bryce, Cyralene P.; Zichlin, Miriam L.; Waber, Deborah P.; Exner, Natalie; Fitzmaurice, Garrett M.; Costa, Paul T. – Journal of Child Psychology and Psychiatry, 2013
Background: Early childhood malnutrition is associated with cognitive and behavioral impairment during childhood and adolescence, but studies in adulthood are limited. Methods: Using the NEO-PI-R personality inventory, we compared personality profiles at 37-43 years of age ("M" 40.3 years, "SD" 1.9) of Barbadian adults who had…
Descriptors: Nutrition, Child Development, Disadvantaged Environment, Personality Traits
Cluver, Lucie D.; Orkin, Mark; Gardner, Frances; Boyes, Mark E. – Journal of Child Psychology and Psychiatry, 2012
Background: By 2008, 12 million children in sub-Saharan Africa were orphaned by AIDS. Cross-sectional studies show psychological problems for AIDS-orphaned children, but until now no longitudinal study has explored enduring psychological effects of AIDS-orphanhood in the developing world. Methods: A 4-year longitudinal follow-up of AIDS-orphaned…
Descriptors: Control Groups, Posttraumatic Stress Disorder, Mental Health, Foreign Countries
Scheeren, Anke M.; de Rosnay, Marc; Koot, Hans M.; Begeer, Sander – Journal of Child Psychology and Psychiatry, 2013
Background: The sociocommunicative problems in autism spectrum disorder (ASD) are traditionally linked to impairments in Theory of Mind (ToM), the ability to ascribe mental states to others. Although ToM impairments are consistently reported in young children with ASD, findings on more advanced ToM understanding in older individuals with…
Descriptors: Pervasive Developmental Disorders, Autism, Theory of Mind, Children
Schwenck, Christina; Mergenthaler, Julia; Keller, Katharina; Zech, Julie; Salehi, Sarah; Taurines, Regina; Romanos, Marcel; Schecklmann, Martin; Schneider, Wolfgang; Warnke, Andreas; Freitag, Christine M. – Journal of Child Psychology and Psychiatry, 2012
Background: A deficit in empathy is discussed to underlie difficulties in social interaction of children with autism spectrum disorder (ASD) and conduct disorder (CD). To date, no study has compared children with ASD and different subtypes of CD to describe disorder-specific empathy profiles in clinical samples. Furthermore, little is known about…
Descriptors: Autism, Perspective Taking, Interpersonal Relationship, Interaction
Tseng, Wan-Ling; Gau, Susan Shur-Fen – Journal of Child Psychology and Psychiatry, 2013
Background: Cognitive processes and mechanisms underlying the strong link between attention-deficit/hyperactivity disorder (ADHD) and social problems remain unclear. Limited knowledge also exists regarding a subgroup of youth with ADHD who do not have social problems. This study investigated the extent to which executive function (EF) mediated the…
Descriptors: Executive Function, Cognitive Processes, Attention Deficit Hyperactivity Disorder, Interpersonal Competence
Burgoyne, Kelly; Duff, Fiona J.; Clarke, Paula J.; Buckley, Sue; Snowling, Margaret J.; Hulme, Charles – Journal of Child Psychology and Psychiatry, 2012
Background: This study evaluates the effects of a language and literacy intervention for children with Down syndrome. Methods: Teaching assistants (TAs) were trained to deliver a reading and language intervention to children in individual daily 40-min sessions. We used a waiting list control design, in which half the sample received the…
Descriptors: Receptive Language, Foreign Countries, Early Intervention, Language Skills
Ouellet-Morin, Isabelle; Tremblay, Richard E.; Boivin, Michel; Meaney, Michael; Kramer, Michael; Cote, Sylvana M. – Journal of Child Psychology and Psychiatry, 2010
Background: Previous studies indicate that children may experience disrupted cortisol secretion in child care. The extent to which this is a transient or long-term disruption is not known, as most studies have relied on cross-sectional designs, and age-heterogeneous small sample sizes. This study aims to (a) compare cortisol secretion measured at…
Descriptors: Pregnancy, Socioeconomic Background, Child Care, Toddlers
Weng, Shih-Jen; Carrasco, Melisa; Swartz, Johnna R.; Wiggins, Jillian Lee; Kurapati, Nikhil; Liberzon, Israel; Risi, Susan; Lord, Catherine; Monk, Christopher S. – Journal of Child Psychology and Psychiatry, 2011
Background: Autism spectrum disorders (ASD) involve a core deficit in social functioning and impairments in the ability to recognize face emotions. In an emotional faces task designed to constrain group differences in attention, the present study used functional MRI to characterize activation in the amygdala, ventral prefrontal cortex (vPFC), and…
Descriptors: Control Groups, Reaction Time, Autism, Adolescents
Keenan, Kate; Feng, Xin; Hipwell, Alison; Klostermann, Susan – Journal of Child Psychology and Psychiatry, 2009
Background: The high comorbidity between depressive and anxiety disorders, especially among females, has called into question the independence of these two symptom groups. It is possible that childhood anxiety typically precedes depression in girls. Comparing of the predictive utility of symptoms of anxiety with the predictive utility of symptoms…
Descriptors: Females, Early Adolescents, Young Children, Depression (Psychology)
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