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Nigg, Joel T.; Craver, Lindsay – Journal of Child Psychology and Psychiatry, 2014
In the 1950's, many experts believed hyperkinesis was a neurotic reaction to inner conflicts arising from early family experiences. In the 1990's, many experts believed ADHD to be "genetic" (without a mechanistic explanation of what that meant). Both views appear naïve today in a scientific world grappling with the complexity…
Descriptors: Attention Deficit Hyperactivity Disorder, Genetic Disorders, Genetics, Psychopathology
Belsky, Jay – Journal of Child Psychology and Psychiatry, 2014
In light of continuing disagreement, even at the meta-analytic level, as to whether the gene- × -environment (G×E) interaction involving 5-HTTLPR and stressful life events (SLEs) predicts depression, Bogdan and associates (this issue, Bogdan et al., 2014) sought to extend research on what has become a highly controversial general (GxE) and…
Descriptors: Genetics, Environment, Experience, Depression (Psychology)
Merker, Sören; Reif, Andreas; Ziegler, Georg C.; Weber, Heike; Mayer, Ute; Ehlis, Ann-Christine; Conzelmann, Annette; Johansson, Stefan; Müller-Reible, Clemens; Nanda, Indrajit; Haaf, Thomas; Ullmann, Reinhard; Romanos, Marcel; Fallgatter, Andreas J.; Pauli, Paul; Strekalova, Tatyana; Jansch, Charline; Vasquez, Alejandro Arias; Haavik, Jan; Ribasés, Marta; Ramos-Quiroga, Josep Antoni; Buitelaar, Jan K.; Franke, Barbara; Lesch, Klaus-Peter – Journal of Child Psychology and Psychiatry, 2017
Background: Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental disorder with profound cognitive, behavioral, and psychosocial impairments with persistence across the life cycle. Our initial genome-wide screening approach for copy number variants (CNVs) in ADHD implicated a duplication of…
Descriptors: Attention Deficit Hyperactivity Disorder, Neurological Impairments, Genetic Disorders, Physiology
Wang, Zhe; Hart, Sara Ann; Kovas, Yulia; Lukowski, Sarah; Soden, Brooke; Thompson, Lee A.; Plomin, Robert; McLoughlin, Grainne; Bartlett, Christopher W.; Lyons, Ian M.; Petrill, Stephen A. – Journal of Child Psychology and Psychiatry, 2014
Background: Emerging work suggests that academic achievement may be influenced by the management of affect as well as through efficient information processing of task demands. In particular, mathematical anxiety has attracted recent attention because of its damaging psychological effects and potential associations with mathematical problem solving…
Descriptors: Mathematics Anxiety, Genetics, Environmental Influences, Multivariate Analysis
Cents, Rolieke A. M.; Kok, Rianne; Tiemeier, Henning; Lucassen, Nicole; Székely, Eszter; Bakermans-Kranenburg, Marian J.; Hofman, Albert; Jaddoe, Vincent W. V.; IJzendoorn, Marinus H.; Verhulst, Frank C.; Lambregtse-van den Berg, Mijke P. – Journal of Child Psychology and Psychiatry, 2014
Background: Little is known about the genetic determinants of sensitive parenting. Two earlier studies examined the effect of the serotonin transporter polymorphism (5-HTTLPR) on sensitive parenting, but reported opposite results. In a large cohort we further examined whether 5-HTTLPR is a predictor of observed maternal sensitivity and whether…
Descriptors: Child Rearing, Mothers, Genetics, Fear
Cognitive and Adaptive Advantages of Growth Hormone Treatment in Children with Prader-Willi Syndrome
Dykens, Elisabeth M.; Roof, Elizabeth; Hunt-Hawkins, Hailee – Journal of Child Psychology and Psychiatry, 2017
Background: People with Prader-Willi syndrome (PWS) typically have mild to moderate intellectual deficits, compulsivity, hyperphagia, obesity, and growth hormone deficiencies. Growth hormone treatment (GHT) in PWS has well-established salutatory effects on linear growth and body composition, yet cognitive benefits of GHT, seen in other patient…
Descriptors: Genetic Disorders, Therapy, Cognitive Ability, Adjustment (to Environment)
Albrecht, Björn; Brandeis, Daniel; Uebel-von Sandersleben, Henrik; Valko, Lilian; Heinrich, Hartmut; Xu, Xiaohui; Drechsler, Renate; Heise, Alexander; Kuntsi, Jonna; Müller, Ueli C.; Asherson, Philip; Steinhausen, Hans-Christoph; Rothenberger, Aribert; Banaschewski, Tobias – Journal of Child Psychology and Psychiatry, 2014
Background: Difficulties with performance and brain activity related to attentional orienting (Cue-P3), cognitive or response preparation (Cue-CNV) and inhibitory response control (Nogo-P3) during tasks tapping executive functions are familial in ADHD and may represent endophenotypes. The aim of this study was to clarify the impact of dopamine…
Descriptors: Attention Deficit Hyperactivity Disorder, Genetics, Responses, Inhibition
Smith, Andrea D.; Herle, Moritz; Fildes, Alison; Cooke, Lucy; Steinsbekk, Silje; Llewellyn, Clare H. – Journal of Child Psychology and Psychiatry, 2017
Background: "Food fussiness" (FF) is the tendency to be highly selective about which foods one is willing to eat, and emerges in early childhood; "food neophobia" (FN) is a closely related characteristic but specifically refers to rejection of unfamiliar food. These behaviors are associated, but the extent to which their…
Descriptors: Food, Fear, Genetics, Environmental Influences
Hayiou-Thomas, Marianna E.; Carroll, Julia M.; Leavett, Ruth; Hulme, Charles; Snowling, Margaret J. – Journal of Child Psychology and Psychiatry, 2017
Background: This study considers the role of early speech difficulties in literacy development, in the context of additional risk factors. Method: Children were identified with speech sound disorder (SSD) at the age of 3½ years, on the basis of performance on the Diagnostic Evaluation of Articulation and Phonology. Their literacy skills were…
Descriptors: Genetics, Risk, Dyslexia, Correlation
Thompson, Paul A.; Hulme, Charles; Nash, Hannah M.; Gooch, Debbie; Hayiou-Thomas, Emma; Snowling, Margaret J. – Journal of Child Psychology and Psychiatry, 2015
Background: Causal theories of dyslexia suggest that it is a heritable disorder, which is the outcome of multiple risk factors. However, whether early screening for dyslexia is viable is not yet known. Methods: The study followed children at high risk of dyslexia from preschool through the early primary years assessing them from age 3 years and 6…
Descriptors: Dyslexia, At Risk Persons, Young Children, Genetic Disorders
Viding, Essi – Journal of Child Psychology and Psychiatry, 2013
Psychologists and psychiatrists have long been aware that individuals differ in their response to environmental stressors. It is equally apparent that whilst positive or corrective environmental factors help some individuals, others seem to benefit little, if at all. To make the matters even more interesting (at least for a researcher who is…
Descriptors: Psychiatry, Stress Variables, Environmental Influences, Genetics
Larsson, Henrik; Anckarsater, Henrik; Rastam, Maria; Chang, Zheng; Lichtenstein, Paul – Journal of Child Psychology and Psychiatry, 2012
Background: Although the clinical utility of categorically defined attention-deficit hyperactivity disorder (ADHD) is well established, there is also strong evidence supporting the notion of ADHD as an extreme of a continuous trait. Nevertheless, the question of whether the etiology is the same for different levels of DSM-IV ADHD symptoms remains…
Descriptors: Attention Deficit Hyperactivity Disorder, Twins, Incidence, Genetics
Lewis, Gary J.; Asbury, Kathryn; Plomin, Robert – Journal of Child Psychology and Psychiatry, 2017
Background: Childhood behavior problems predict subsequent educational achievement; however, little research has examined the etiology of these links using a longitudinal twin design. Moreover, it is unknown whether genetic and environmental innovations provide incremental prediction for educational achievement from childhood to adolescence.…
Descriptors: Behavior Problems, Academic Achievement, Prediction, Peer Relationship
Tye, Charlotte; Rijsdijk, Fruhling; Greven, Corina U.; Kuntsi, Jonna; Asherson, Philip; McLoughlin, Grainne – Journal of Child Psychology and Psychiatry, 2012
Background: Attention deficit hyperactivity disorder (ADHD) is a common and highly heritable neurodevelopmental disorder with a complex aetiology. The identification of candidate intermediate phenotypes that are both heritable and genetically linked to ADHD may facilitate the detection of susceptibility genes and elucidate aetiological pathways.…
Descriptors: Attention Deficit Hyperactivity Disorder, Twins, Genetics, Genetic Disorders
Silberg, Judy L.; Maes, Hermine; Eaves, Lindon J. – Journal of Child Psychology and Psychiatry, 2012
Background: A critical issue in devising effective interventions for the treatment of children's behavioral and emotional problems identifying genuine family environmental factors that place children at risk. In most twin and family studies, environmental factors are confounded with both direct genetic risk from parents and the indirect effect of…
Descriptors: Emotional Problems, Twins, Parent Influence, Hyperactivity