Counselors, psychologists, and evaluators of intervention programs for youth increasingly view the promotion of connectedness as an important intervention outcome. When evaluating these programs, researchers frequently test whether the treatment effects differ across gender and ethnic or racial groups. Doing so necessitates the availability of culturally and gender-invariant measures. We used the Hemingway: Measure of Adolescent Connectedness to estimate the factor structure invariance and equality of means across gender and 3 racial/ethnic groups with a large sample of middle school adolescents. From a practical perspective, the 10-scale model suggested factor structure invariance across gender and racial or ethnic (i.e., African American, Caucasian, and Latina/o) groups of adolescents. However, tests for partial invariance revealed some group difference on the factor loadings and intercepts between gender and ethnic/racial groups. When testing for mean equivalence, girls reported higher connectedness to friends, siblings, school, peers, teachers, and reading but lower connectedness to their neighborhoods. Caucasians reported higher connectedness to their neighborhoods and friends but lower connectedness to siblings than African Americans and Latinos. African Americans reported the highest connectedness to self (present and future) but lowest connectedness to teachers. Latinos reported the lowest connectedness to reading, self-in-the-present, and self-in-the-future. Overall, this study reveals racial/ethnic and gender mean differences on several connectedness subscales and suggests the Hemingway subscales are, from a practical perspective, invariant across gender and ethnicity and therefore appropriate for most assessment and evaluation purposes. (Contains 2 footnotes, 7 tables, and 2 figures.)