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Direct linkRoy, A.; Roy, M.; Deb, S.; Unwin, G.; Roy, A. – Journal of Intellectual Disability Research, 2015
Background: ASC (autism spectrum conditions) may result from a failure of striatal beta endorphins to diminish with maturation. Many symptoms of ASC resemble behaviours induced in animals or humans by opiate administration, including decreased socialisation, diminished crying, repetitive stereotypies, insensitivity to pain and motor hyperactivity.…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Behavior Problems
Lovell, B.; Moss, M.; Wetherell, M. A. – Journal of Intellectual Disability Research, 2015
Background: The positive relationship between problem behaviours of children with additional complex needs and psychological distress in their caregivers has been widely evidenced. Fewer studies, however, have assessed the relationship between care recipients' problem behaviours and key physiological processes, relevant for the physical…
Descriptors: Correlation, Behavior Problems, Psychology, Psychological Patterns
Quality of Life and Psychological Well-Being in GH-Treated, Adult PWS Patients: A Longitudinal Study
Bertella, L.; Mori, I.; Grugni, G.; Pignatti, R.; Ceriani, F.; Molinari, E.; Ceccarelli, A.; Sartorio, A.; Vettor, R.; Semenza, C. – Journal of Intellectual Disability Research, 2007
Background: Prader-Willi syndrome (PWS) is a congenital alteration of chromosome pair 15. It is characterized by short stature, muscular hypotonia, hyperphagia, obesity, behavioural and emotional disturbances, hypogonadism and partial Growth Hormone (GH) deficiency. The aim of this study was to assess the long-term effect of GH treatment on the…
Descriptors: Questionnaires, Psychology, Patients, Intervals
