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Direct linkRockers, K.; Ousley, O.; Sutton, T.; Schoenberg, E.; Coleman, K.; Walker, E.; Cubells, J. F. – Journal of Intellectual Disability Research, 2009
Background: Approximately one-third of individuals with 22q11.2 deletion syndrome (22q11DS), a common genetic disorder highly associated with intellectual disabilities, may develop schizophrenia, likely preceded by a mild to moderate cognitive decline. Methods: We examined adolescents and young adults with 22q11DS for the presence of executive…
Descriptors: Genetic Disorders, Mental Retardation, Schizophrenia, Psychopathology
El Tahir, M. O.; Kerr, M.; Jones, R. G. – Journal of Intellectual Disability Research, 2004
Velocardiofacial syndrome (VCFS) is caused by a micro deletion of chromosome 22q11 and associated with multiple system abnormalities. There is an increasing recognition of associations with psychiatric disorders. Neurological and brain abnormalities have been reported but to date no association with generalized epilepsy has been reported in…
Descriptors: Investigations, Seizures, Schizophrenia, Epilepsy
Roberts, J. E.; Symons, F. J.; Johnson, A.-M.; Hatton, D. D.; Boccia, M. L. – Journal of Intellectual Disability Research, 2005
Background: Dopamine, a neurotransmitter involved in motor and cognitive functioning, can be non-invasively measured via observation of spontaneous blink rates. Blink rates have been studied in a number of clinical conditions including schizophrenia, autism, Parkinsons, and attention deficit/hyperactivity disorder with results implicating either…
Descriptors: Schizophrenia, Males, Hyperactivity, Mental Retardation
