The authors sought to modify and apply Pearlin et al.'s "Stress and Coping Framework" model (which was designed to guide research on family caregiving) to research that could help them understand the experiences of staff carers of persons with intellectual disabilities affected by dementia. The authors, two experienced researchers and practitioners in intellectual disabilities and dementia, reviewed the existing literature on the "Stress and Coping Framework" model, as well as additional literature on family and staff caregiving for persons with dementia and intellectual disabilities, in an attempt to identify the model's key variables and to determine whether these variables could be applied to research with staff. They determined that the domains of the "Stress and Coping Framework" model appeared relevant for staff carer research; but proposed changes in some of the variables defining those domains (e.g., some of the original demographic variables were dropped as less important for staff carers and some organizational variables are added). The authors concluded that with modification, Pearlin et al.'s model of stress and coping is a useful guide to support research on the experiences of staff carers of persons with intellectual disabilities affected by dementia. To this end, they have proposed a modified "Stress and Coping Framework" structure that can be applied to research in the area of staff burden.