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Doyle, Alysa E.; Biederman, Joseph; Ferreira, Manuel A. R.; Wong, Patricia; Smoller, Jordan W.; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Several studies have documented a profile of elevated scores on the Attention Problems, Aggressive Behavior and Anxious/Depressed scales of the Child Behavior Checklist (CBCL) in youth with bipolar disorder. The sum of these scales, referred to as the CBCL Juvenile Bipolar Disorder (JBD) phenotype, has modest diagnostic utility, and…
Descriptors: Check Lists, Siblings, Aggression, Schizophrenia
Albaugh, Matthew D.; Harder, Valerie S.; Althoff, Robert R.; Rettew, David C.; Ehli, Erik A.; Lengyel-Nelson, Timea; Davies, Gareth E.; Ayer, Lynsay; Sulman, Julie; Stanger, Catherine; Hudziak, James J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To test the association between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and both aggressive behavior and attention problems in youth. We hypothesized that youth carrying a Met allele would have greater average aggressive behavior scores, and that youth exhibiting Val-homozygosity would have greater average…
Descriptors: Behavior Problems, Aggression, Attention, Genetics
Pardini, Dustin; Stepp, Stephanie; Hipwell, Alison; Stouthamer-Loeber, Magda; Loeber, Rolf – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: A callous-unemotional (CU) subtype of conduct disorder (CD) has been proposed as an addition to the fifth edition of the "Diagnostic and Statistic Manual of Mental Disorders (DSM-5)." This study tested the hypothesis that young girls with the CU subtype of CD would exhibit more severe antisocial behavior and less severe internalizing…
Descriptors: Attention Deficit Hyperactivity Disorder, Antisocial Behavior, Females, Mental Disorders
Monuteaux, Michael C.; Biederman, Joseph; Doyle, Alysa E.; Mick, Eric; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
Four hundred forty-four subjects aged 6-55 years were evaluated to examine the role of COMT and SLC6A4 genes in the risk for conduct disorder and its symptomatic subtypes in the context of attention deficit hyperactivity disorder. No significant association is found between these genes and the risk for conduct disorder.
Descriptors: Hyperactivity, Attention Deficit Disorders, Behavior Problems, Genetics
Mick, Eric; McGough, James; Loo, Sandra; Doyle, Alysa E.; Wozniak, Janet; Wilens, Timothy E.; Smalley, Susan; McCracken, James; Biederman, Joseph; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: A potentially useful tool for understanding the distribution and determinants of emotional dysregulation in children is a Child Behavior Checklist profile, comprising the Attention Problems, Anxious/Depressed, and Aggressive Behavior clinical subscales (CBCL-DP). The CBCL-DP indexes a heritable trait that increases susceptibility for…
Descriptors: Attention Deficit Hyperactivity Disorder, Check Lists, Aggression, Psychopathology
Stringaris, Argyris; Goodman, Robert – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
A longitudinal design that compares data from two British national surveys and their follow-ups reveal that an irritable dimension of oppositional behavior is the sole predictor of emotional disorder at follow-up. The headstrong dimension is the predictor of attention-deficit hyperactivity disorder while the hurtful dimension is a strong predictor…
Descriptors: Aggression, Longitudinal Studies, Comparative Analysis, Foreign Countries
Jester, Jennifer M.; Nigg, Joel T.; Buu, Anne; Puttler, Leon I.; Glass, Jennifer M.; Heitzeg, Mary M.; Fitzgerald, Hiram E.; Zucker, Robert A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
335 children of alcoholic and nonalcoholic fathers were examined to study the relation between childhood behavior trajectories and adolescent substance abuse. Findings suggested that children with both aggression and inattention/hyperactivity were at an increased risk of substance abuse when compared to children with only inattention/hyperactivity…
Descriptors: Substance Abuse, Hyperactivity, Drug Use, Adolescents
Armenteros, Jorge L.; Lewis, John E.; Davalos, Marisabel – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To evaluate the effects of risperidone augmentation for treatment-resistant aggression in children with attention-deficit/hyperactivity disorder (ADHD). Method: Twenty-five children (ages 7-12 years) with attention-deficit/hyperactivity disorder(ADHD) and significant aggressive behaviors were randomized to risperidone or placebo for 4…
Descriptors: Hyperactivity, Aggression, Attention Deficit Disorders, Drug Therapy
Gorman, Erin B.; Klorman, Rafael; Thatcher, Joan E.; Borgstedt, Agneta D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2006
Objective: To compare the effects of methylphenidate on attention-deficit/hyperactivity disorder (ADHD) subtypes. Method: Nineteen ADHD/inattentive (ADHD/I) and 22 ADHD/combined (ADHD/C) 6- to 12-year-old children entered a 6-week, double-blind trial of placebo and methylphenidate in divided doses (0.94 [plus or minus] 0.02 mg/kg/day = 33.06 [plus…
Descriptors: Attention Deficit Hyperactivity Disorder, Arithmetic, Drug Therapy, Outcomes of Treatment
Carlson, Teri; Reynolds, Charles A.; Caplan, Rochelle – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
This case report describes two children who developed hyperammonemia together with frank manic behavior during treatment with a combination of valproic acid and risperidone. One child had been maintained on valproic acid for years and risperidone was added. In the second case, valproic acid was introduced to a child who had been treated with…
Descriptors: Drug Therapy, Symptoms (Individual Disorders), Children, Psychiatry
Findling, Robert L.; Newcorn, Jeffrey H.; Malone, Richard P.; Waheed, Ayesha; Prince, Jefferson B.; Kratochvil, Christopher J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
A 9-year-old boy presents for assessment and treatment of his reactive, impulsive aggressive behavior that has been present for approximately 2 years. Six months ago, his pediatrician started treatment with OROS methylphenidate (MPH), which was titrated to 36 mg/day. There was moderate improvement in symptoms of attention-deficit/hyperactivity…
Descriptors: Hyperactivity, Aggression, Attention Deficit Disorders, Drug Therapy
Hughes, Carroll W.; Emslie, Graham J.; Crismon, M. Lynn; Posner, Kelly; Birmaher, Boris; Ryan, Neal; Jensen, Peter; Curry, John; Vitiello, Benedetto; Lopez, Molly; Shon, Steve P.; Pliszka, Steven R.; Trivedi, Madhukar H. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To revise and update consensus guidelines for medication treatment algorithms for childhood major depressive disorder based on new scientific evidence and expert clinical consensus when evidence is lacking. Method: A consensus conference was held January 13-14, 2005, that included academic clinicians and researchers, practicing…
Descriptors: Guidelines, Psychosis, Depression (Psychology), Clinical Experience
Jensen, Peter S.; Youngstrom, Eric A.; Steiner, Hans; Findling, Robert L.; Meyer, Roger E.; Malone, Richard P.; Carlson, Gabrielle A.; Coccaro, Emil F.; Aman, Michael G.; Blair, James; Dougherty, Donald; Ferris, Craig; Flynn, Laurie; Green, Evelyn; Hoagwood, Kimberly; Hutchinson, Janice; Laughren, Tom; Leve, Leslie D.; Novins, Douglas K.; Vitiello, Benedetto – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To determine whether impulsive aggression (IA) is a meaningful clinical construct and to ascertain whether it is sufficiently similar across diagnostic categories, such that parallel studies across disorders might constitute appropriate evidence for pursuing indications. If so, how should IA be assessed, pharmacological studies…
Descriptors: Psychiatry, Public Health, Ethics, Clinical Experience
Pliszka, Steven R.; Crismon, M. Lynn; Hughes, Carroll W.; Corners, C. Keith; Emslie, Graham J.; Jensen, Peter S.; McCracken, James T.; Swanson, James M.; Lopez, Molly – Journal of the American Academy of Child & Adolescent Psychiatry, 2006
Objective: In 1998, the Texas Department of Mental Health and Mental Retardation developed algorithms for medication treatment of attention-deficit/hyperactivity disorder (ADHD). Advances in the psychopharmacology of ADHD and results of a feasibility study of algorithm use in community mental health centers caused the algorithm to be modified and…
Descriptors: Attention Deficit Hyperactivity Disorder, Feasibility Studies, Mental Health, Pharmacology