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Direct linkKahn, Julia B.; Ward, Ryan D.; Kahn, Lora W.; Rudy, Nicole M.; Kandel, Eric R.; Balsam, Peter D.; Simpson, Eleanor H. – Learning & Memory, 2012
Working memory and attention are complex cognitive functions that are disrupted in several neuropsychiatric disorders. Mouse models of such human diseases are commonly subjected to maze-based tests that can neither distinguish between these cognitive functions nor isolate specific aspects of either function. Here, we have adapted a simple visual…
Descriptors: Animals, Maintenance, Visual Discrimination, Short Term Memory
Peters, Gregory J.; David, Christopher N.; Marcus, Madison D.; Smith, David M. – Learning & Memory, 2013
The prefrontal cortex (PFC) is known to be critically involved in strategy switching, attentional set shifting, and inhibition of prepotent responses. A central feature of this kind of behavioral flexibility is the ability to resolve conflicting response tendencies, suggesting a general role of the PFC in resolving interference. If so, the PFC…
Descriptors: Memory, Tests, Olfactory Perception, Interference (Learning)
