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Direct linkJones, Carolyn E.; Monfils, Marie-H. – Learning & Memory, 2016
Traumatic experiences early in life can contribute to the development of mood and anxiety disorders that manifest during adolescence and young adulthood. In young rats exposed to acute fear or stress, alterations in neural development can lead to enduring behavioral abnormalities. Here, we used a modified extinction intervention…
Descriptors: Adolescents, Fear, Juvenile Justice, Classical Conditioning
Soeter, Marieke; Kindt, Merel – Learning & Memory, 2011
We previously demonstrated that disrupting reconsolidation by pharmacological manipulations "deleted" the emotional expression of a fear memory in humans. If we are to target reconsolidation in patients with anxiety disorders, the disruption of reconsolidation should produce content-limited modifications. At the same time, the fear-erasing effects…
Descriptors: Anxiety Disorders, Patients, Memory, Generalization
Costanzi, Marco; Cannas, Sara; Saraulli, Daniele; Rossi-Arnaud, Clelia; Cestari, Vincenzo – Learning & Memory, 2011
Long-lasting memories of adverse experiences are essential for individuals' survival but are also involved, in the form of recurrent recollections of the traumatic experience, in the aetiology of anxiety diseases (e.g., post-traumatic stress disorder [PTSD]). Extinction-based erasure of fear memories has long been pursued as a behavioral way to…
Descriptors: Behavior Modification, Therapy, Child Abuse, Posttraumatic Stress Disorder
