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Loiotile, Rita E.; Courtney, Susan M. – Learning & Memory, 2015
Behavioral pattern separation (BPS) paradigms ask participants to discriminate previously encoded (old) stimuli from highly similar (lure) and categorically distinct (novel) stimuli. The lure-old discrimination, thought to uniquely reflect pattern separation in the hippocampal formation, is typically pitted against the traditional novel-old…
Descriptors: Behavioral Science Research, Stimuli, Novelty (Stimulus Dimension), Familiarity
Linster, Christiane; Menon, Alka V.; Singh, Christopher Y.; Wilson, Donald A. – Learning & Memory, 2009
Segmentation of target odorants from background odorants is a fundamental computational requirement for the olfactory system and is thought to be behaviorally mediated by olfactory habituation memory. Data from our laboratory have shown that odor-specific adaptation in piriform neurons, mediated at least partially by synaptic adaptation between…
Descriptors: Memory, Habituation, Brain, Interaction