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Vousden, George H.; Paulcan, Sloane; Robbins, Trevor W.; Eagle, Dawn M.; Milton, Amy L. – Learning & Memory, 2020
In obsessive-compulsive disorder (OCD), functional behaviors such as checking that a door is locked become dysfunctional, maladaptive, and debilitating. However, it is currently unknown how aversive and appetitive motivations interact to produce functional and dysfunctional behavior in OCD. Here we show a double dissociation in the effects of…
Descriptors: Animal Behavior, Cues, Task Analysis, Punishment
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Amano, Hisayuki; Maruyama, Ichiro N. – Learning & Memory, 2011
The nematode "Caenorhabditis elegans" ("C. elegans") adult hermaphrodite has 302 invariant neurons and is suited for cellular and molecular studies on complex behaviors including learning and memory. Here, we have developed protocols for classical conditioning of worms with 1-propanol, as a conditioned stimulus (CS), and hydrochloride (HCl) (pH…
Descriptors: Stimuli, Classical Conditioning, Long Term Memory, Olfactory Perception