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Mechie, Imogen R.; Plaisted-Grant, Kate; Cheke, Lucy G. – Learning & Memory, 2021
Key areas of the episodic memory (EM) network demonstrate changing structure and volume during adolescence. EM is multifaceted and yet studies of EM thus far have largely examined single components, used different methods and have unsurprisingly yielded inconsistent results. The Treasure Hunt task is a single paradigm that allows parallel…
Descriptors: Memory, Adolescents, Cognitive Development, Brain Hemisphere Functions
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Bisaz, Reto; Bessières, Benjamin; Miranda, Janelle M.; Travaglia, Alessio; Alberini, Cristina M. – Learning & Memory, 2021
Episodic memories formed during infancy are rapidly forgotten, a phenomenon associated with infantile amnesia, the inability of adults to recall early-life memories. In both rats and mice, infantile memories, although not expressed, are actually stored long term in a latent form. These latent memories can be reinstated later in life by certain…
Descriptors: Recall (Psychology), Infants, Long Term Memory, Adults
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Butler, Christopher W.; Keiser, Ashley A.; Kwapis, Janine L.; Berchtold, Nicole C.; Wall, Vanessa L.; Wood, Marcelo A.; Cotman, Carl W. – Learning & Memory, 2019
The beneficial effects of exercise on cognition are well established; however specific exercise parameters regarding the frequency and duration of physical activity that provide optimal cognitive health have not been well defined. Here, we explore the effects of the duration of exercise and sedentary periods on long-term object location memory…
Descriptors: Exercise, Cognitive Development, Physical Activities, Memory
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Bessières, Benjamin; Jia, Margaret; Travaglia, Alessio; Alberini, Cristina M. – Learning & Memory, 2019
The basolateral complex of amygdala (BLA) processes emotionally arousing aversive and rewarding experiences. The BLA is critical for acquisition and storage of threat-based memories and the modulation of the consolidation of arousing explicit memories, that is, the memories that are encoded and stored by the medial temporal lobe. In addition, in…
Descriptors: Brain, Animals, Memory, Individual Development
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Skalaban, Lena J.; Cohen, Alexandra O.; Conley, May I.; Lin, Qi; Schwartz, Garrett N.; Ruiz-Huidobro, Nicholas A. M.; Cannonier, Tariq; Martinez, Steven A.; Casey, B. J. – Learning & Memory, 2022
Working memory and recognition memory develop across adolescence, but the relationship between them is not fully understood. We investigated associations between n-back task performance and subsequent recognition memory in a community sample (8-30 yr, n = 150) using tasks from the Adolescent Brain Cognitive Development Study (ABCD Study) to…
Descriptors: Adolescents, Short Term Memory, Recognition (Psychology), Adults
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Stern, Sarah A.; Chen, Dillon Y.; Alberini, Cristina M. – Learning & Memory, 2014
Recent work has reported that the insulin-like growth factor 2 (IGF2) promotes memory enhancement. Furthermore, impaired insulin or IGF1 functions have been suggested to play a role in the pathogenesis of neurodegeneration and cognitive impairments, hence implicating the insulin/IGF system as an important target for cognitive enhancement and/or…
Descriptors: Memory, Drug Use, Neurological Impairments, Cognitive Development
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Leach, Prescott T.; Poplawski, Shane G.; Kenney, Justin W.; Hoffman, Barbara; Liebermann, Dan A.; Abel, Ted; Gould, Thomas J. – Learning & Memory, 2012
Growth arrest and DNA damage-inducible [beta] ("Gadd45b") has been shown to be involved in DNA demethylation and may be important for cognitive processes. "Gadd45b" is abnormally expressed in subjects with autism and psychosis, two disorders associated with cognitive deficits. Furthermore, several high-throughput screens have identified "Gadd45b"…
Descriptors: Genetics, Brain, Animals, Fear