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Direct linkPu, Lu; Kopec, Ashley M.; Boyle, Heather D.; Carew, Thomas J. – Learning & Memory, 2014
Neurotrophins are critically involved in developmental processes such as neuronal cell survival, growth, and differentiation, as well as in adult synaptic plasticity contributing to learning and memory. Our previous studies examining neurotrophins and memory formation in "Aplysia" showed that a TrkB ligand is required for MAPK…
Descriptors: Brain, Memory, Learning Processes, Neurological Organization
Sehgal, Megha; Ehlers, Vanessa L.; Moyer, James R., Jr. – Learning & Memory, 2014
Learning-induced modulation of neuronal intrinsic excitability is a metaplasticity mechanism that can impact the acquisition of new memories. Although the amygdala is important for emotional learning and other behaviors, including fear and anxiety, whether learning alters intrinsic excitability within the amygdala has received very little…
Descriptors: Learning Processes, Neurological Organization, Brain Hemisphere Functions, Fear
Dayan, Eran; Averbeck, Bruno B.; Richmond, Barry J.; Cohen, Leonardo G. – Learning & Memory, 2014
Learning complex skills is driven by reinforcement, which facilitates both online within-session gains and retention of the acquired skills. Yet, in ecologically relevant situations, skills are often acquired when mapping between actions and rewarding outcomes is unknown to the learning agent, resulting in reinforcement schedules of a stochastic…
Descriptors: Visual Perception, Psychomotor Skills, Reinforcement, Training Methods
Oros, Nicolas; Chiba, Andrea A.; Nitz, Douglas A.; Krichmar, Jeffrey L. – Learning & Memory, 2014
Learning to ignore irrelevant stimuli is essential to achieving efficient and fluid attention, and serves as the complement to increasing attention to relevant stimuli. The different cholinergic (ACh) subsystems within the basal forebrain regulate attention in distinct but complementary ways. ACh projections from the substantia innominata/nucleus…
Descriptors: Stimuli, Cognitive Processes, Attention, Brain Hemisphere Functions
Hindley, Emma L.; Nelson, Andrew J. D.; Aggleton, John P.; Vann, Seralynne D. – Learning & Memory, 2014
The retrosplenial cortex supports navigation, with one role thought to be the integration of different spatial cue types. This hypothesis was extended by examining the integration of nonspatial cues. Rats with lesions in either the dysgranular subregion of retrosplenial cortex (area 30) or lesions in both the granular and dysgranular subregions…
Descriptors: Brain Hemisphere Functions, Animals, Cues, Hypothesis Testing
Weinberger, Norman M. – Learning & Memory, 2007
Historically, sensory systems have been largely ignored as potential loci of information storage in the neurobiology of learning and memory. They continued to be relegated to the role of "sensory analyzers" despite consistent findings of associatively induced enhancement of responses in primary sensory cortices to behaviorally important signal…
Descriptors: Memory, Experimental Psychology, Classical Conditioning, Brain
