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Leal, Stephanie L.; Ferguson, Lorena A.; Harrison, Theresa M.; Jagust, William J. – Learning & Memory, 2019
Most tasks test memory within the same day, however, most forgetting occurs after 24 h. Further, testing memory for simple words or objects does not mimic real-world memory experiences. We designed a memory task showing participants video clips of everyday kinds of experiences, including positive, negative, and neutral stimuli, and tested memory…
Descriptors: Memory, Alzheimers Disease, Stimuli, Recognition (Psychology)
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Johnson, Sarah A.; Sacks, Patricia K.; Turner, Sean M.; Gaynor, Leslie S.; Ormerod, Brandi K.; Maurer, Andrew P.; Bizon, Jennifer L.; Burke, Sara N. – Learning & Memory, 2016
Hippocampal-dependent episodic memory and stimulus discrimination abilities are both compromised in the elderly. The reduced capacity to discriminate between similar stimuli likely contributes to multiple aspects of age-related cognitive impairment; however, the association of these behaviors within individuals has never been examined in an animal…
Descriptors: Brain Hemisphere Functions, Animals, Models, Tests
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Nelson, Andrew J. D.; Hindley, Emma L.; Haddon, Josephine E.; Vann, Seralynne D.; Aggleton, John P. – Learning & Memory, 2014
By virtue of its frontal and hippocampal connections, the retrosplenial cortex is uniquely placed to support cognition. Here, we tested whether the retrosplenial cortex is required for frontal tasks analogous to the Stroop Test, i.e., for the ability to select between conflicting responses and inhibit responding to task-irrelevant cues. Rats first…
Descriptors: Animals, Cognitive Ability, Brain Hemisphere Functions, Correlation