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Direct linkLee, Jonathan L. C.; Everitt, Barry J. – Learning & Memory, 2008
The theory of memory reconsolidation relates to the hypothesized restabilisation process that occurs following the reactivation of a memory through retrieval. Thus, the demonstration of reactivation-dependent amnesia for a previously acquired memory is a prerequisite for showing that such a memory undergoes reconsolidation. Here, we show that the…
Descriptors: Classical Conditioning, Recall (Psychology), Retention (Psychology), Learning Processes
Hupbach, Almut; Hardt, Oliver; Gomez, Rebecca; Nadel, Lynn – Learning & Memory, 2008
Understanding the dynamics of memory change is one of the current challenges facing cognitive neuroscience. Recent animal work on memory reconsolidation shows that memories can be altered long after acquisition. When reactivated, memories can be modified and require a restabilization (reconsolidation) process. We recently extended this finding to…
Descriptors: Recall (Psychology), Neuropsychology, Animals, Experiments
Ramos, Juan M. J. – Learning & Memory, 2008
Several lines of evidence in humans and experimental animals suggest that the hippocampus is critical for the formation and retrieval of spatial memory. However, although the hippocampus is reciprocally connected to adjacent cortices within the medial temporal lobe and they, in turn, are connected to the neocortex, little is known regarding the…
Descriptors: Surgery, Spatial Ability, Animals, Experiments
Dommett, Eleanor J.; Henderson, Emma L.; Westwell, Martin S.; Greenfield, Susan A. – Learning & Memory, 2008
Methylphenidate treatment is used for Attention Deficit Hyperactivity Disorder and can improve learning and memory. Previously, improvements were considered a by-product of increased attention; however, we hypothesize that methylphenidate directly alters mechanisms underlying learning and memory, and therefore examined its effects on hippocampal…
Descriptors: Hyperactivity, Attention Deficit Disorders, Memory, Depression (Psychology)
Turchi, Janita; Buffalari, Deanne; Mishkin, Mortimer – Learning & Memory, 2008
Monkeys trained in either one-trial recognition at 8- to 10-min delays or multi-trial discrimination habits with 24-h intertrial intervals received systemic cholinergic and dopaminergic antagonists, scopolamine and haloperidol, respectively, in separate sessions. Recognition memory was impaired markedly by scopolamine but not at all by…
Descriptors: Habit Formation, Intervals, Discrimination Learning, Visual Discrimination
Laureys, Steven; Degueldre, Christian; Del Fiore, Guy; Aerts, Joel; Luxen, Andre; Van Der Linden, Martial; Cleeremans, Axel; Maquet, Pierre; Destrebecqz, Arnaud; Peigneux, Philippe – Learning & Memory, 2005
In two H[subscript 2] [superscript 15]O PET scan experiments, we investigated the cerebral correlates of explicit and implicit knowledge in a serial reaction time (SRT) task. To do so, we used a novel application of the Process Dissociation Procedure, a behavioral paradigm that makes it possible to separately assess conscious and unconscious…
Descriptors: Learning Processes, Reaction Time, Sequential Learning, Pacing
