During associative retrieval, the brain reinstates neural representations that were present during encoding. The human medial temporal lobe (MTL), with its subregions hippocampus (HC), perirhinal cortex (PRC), and parahippocampal cortex (PHC), plays a central role in neural reinstatement. Previous studies have given compelling evidence for…

When we look at repeated scenes, we tend to visit similar regions each time--a phenomenon known as "resampling." Resampling has long been attributed to episodic memory, but the relationship between resampling and episodic memory has recently been found to be less consistent than assumed. A possibility that has yet to be fully considered…

Visual imagery and mental reconstruction of scenes are considered core components of episodic memory retrieval. Individuals with absent visual imagery (aphantasia) score lower on tests of autobiographical memory, suggesting that aphantasia may be associated with differences in episodic and associative processing. In this online study, we tested…

When our experience violates our predictions, it is adaptive to update our knowledge to promote a more accurate representation of the world and facilitate future predictions. Theoretical models propose that these mnemonic prediction errors should be encoded into a distinct memory trace to prevent interference with previous, conflicting memories.…

The features of an image can be represented at multiple levels--from its low-level visual properties to high-level meaning. What drives some images to be memorable while others are forgettable? We address this question across two behavioral experiments. In the first, different layers of a convolutional neural network (CNN), which represent…

Some previous studies have shown that increased stress hormone levels have beneficial effects on memory encoding; however, there is no clear consensus on which encoding-related processes are affected by stress hormones. In the present study, we investigated the relationship between interindividual differences in neuroendocrine response to acute…

How do we form mental links between related items? Forming associations between representations is a key feature of episodic memory and provides the foundation for learning and guiding behavior. Theories suggest that spatial context plays a supportive role in episodic memory, providing a scaffold on which to form associations, but this has mostly…

According to several computational models, novel items can create a learning mode with dynamics favorable to new learning, and not to memory retrieval. In line with that idea, a new item in a recognition test has been found to create a bias toward calling subsequent items new as well. Here, we tested whether this bias, which we termed the…

According to dual-process theory, recognition memory performance draws upon two processes, familiarity and recollection. The relative contribution to recognition memory are commonly distinguished in humans by analyzing receiver-operating-characteristics (ROC) curves; analogous methods are more complex and very rare in animals but fast familiarity…

Reality-monitoring errors occur when internally generated thoughts are remembered as external occurrences. We hypothesized that sleep-dependent memory consolidation could reduce them by strengthening connections between items and their contexts during an afternoon nap. Participants viewed words and imagined their referents. Pictures of the…

On forced-choice tests of recognition memory, performance is best when targets are paired with novel foils (A-X), followed by corresponding lures (A-A'), and then noncorresponding lures (A-B'). The current study tested the prediction that encoding variability accounts for reduced performance on A-B' trials. Young adults (n = 43) completed the…

There has been considerable focus on investigating age-related memory changes in cognitively healthy older adults, in the absence of neurodegenerative disorders. Previous studies have reported age-related domain-specific changes in older adults, showing increased difficulty encoding and processing object information but minimal to no impairment in…

Research suggests that sleep preferentially consolidates the negative aspects of memories at the expense of the neutral aspects. However, the mechanisms by which sleep facilitates this emotional memory trade-off remain unknown. Although active processes associated with sleep-dependent memory consolidation have been proposed to underlie this…

Mental schemas provide a framework into which new information can easily be integrated. In a series of experiments, we examined how incongruence that stems from a prediction error modulates memory for multicomponent events that instantiated preexisting schemas as noted in a previous study. Each event consisted of four stimulus pairs with…

The hippocampus has long been recognized as important for the formation of long-term memory. Recent work has suggested that the hippocampus might also be important for certain kinds of spatial operations, as in constructing scenes, shifting perspective, or perceiving the geometry of scenes and their boundaries. We explored this proposal using a…