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Direct linkMichel, Maximilian; Green, Charity L.; Lyons, Lisa C. – Learning & Memory, 2011
We investigated the involvement of PKA and PKC signaling in a negatively reinforced operant learning paradigm in "Aplysia", learning that food is inedible (LFI). In vivo injection of PKA or PKC inhibitors blocked long-term LFI memory formation. Moreover, a persistent phase of PKA activity, although not PKC activity, was necessary for long-term…
Descriptors: Long Term Memory, Food, Learning, Models
Diegelmann, Soeren; Zars, Melissa; Zars, Troy – Learning & Memory, 2006
Memories can have different strengths, largely dependent on the intensity of reinforcers encountered. The relationship between reinforcement and memory strength is evident in asymptotic memory curves, with the level of the asymptote related to the intensity of the reinforcer. Although this is likely a fundamental property of memory formation,…
Descriptors: Reinforcement, Models, Memory, Memorization
