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Toner, Chelsea K.; Pirogovsky, Eva; Kirwan, C. Brock; Gilbert, Paul E. – Learning & Memory, 2009
Young and nondemented older adults were tested on a continuous recognition memory task requiring visual pattern separation. During the task, some objects were repeated across trials and some objects, referred to as lures, were presented that were similar to previously presented objects. The lures resulted in increased interference and an increased…
Descriptors: Young Adults, Older Adults, Recognition (Psychology), Memorization
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Janus, Christopher – Learning & Memory, 2004
TgCRND8 mice represent a transgenic mouse model of Alzheimer's disease, with onset of cognitive impairment and increasing amyloid-[beta] plaques in their brains at 12 weeks of age. In this study, the spatial memory in 25- to 30-week-old TgCRND8 mice was analyzed in two reference and one working memory Morris water maze (MWM) tests. In reference…
Descriptors: Pathology, Nonverbal Learning, Spatial Ability, Learning Strategies