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Knutson, Ashley R.; Hopkins, Ramona O.; Squire, Larry R. – Learning & Memory, 2013
We tested proposals that medial temporal lobe (MTL) structures support not just memory but certain kinds of visual perception as well. Patients with hippocampal lesions or larger MTL lesions attempted to identify the unique object among twin pairs of objects that had a high degree of feature overlap. Patients were markedly impaired under the more…
Descriptors: Visual Discrimination, Neurological Impairments, Patients, Memory
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Hales, Jena B.; Broadbent, Nicola J.; Velu, Priya D.; Squire, Larry R.; Clark, Robert E. – Learning & Memory, 2015
Structures in the medial temporal lobe, including the hippocampus and perirhinal cortex, are known to be essential for the formation of long-term memory. Recent animal and human studies have investigated whether perirhinal cortex might also be important for visual perception. In our study, using a simultaneous oddity discrimination task, rats with…
Descriptors: Brain Hemisphere Functions, Animals, Eye Movements, Task Analysis
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Squire, Larry R.; Levy, Daniel A.; Shrager, Yael – Learning & Memory, 2005
The perirhinal cortex is known to be important for memory, but there has recently been interest in the possibility that it might also be involved in visual perceptual functions. In four experiments, we assessed visual discrimination ability and visual discrimination learning in severely amnesic patients with large medial temporal lobe lesions that…
Descriptors: Visual Discrimination, Patients, Discrimination Learning, Memory