Low-income students in college face many challenges, including the cost of postsecondary education and competing demands on their time from work or family obligations. They may not be prepared for college academically. They may also lack the skills and experiences other students rely on to help them navigate college, or the social support that can help them overcome challenges in college. MDRC has developed a deep body of evidence on interventions designed to help low-income college students succeed. This issue brief looks back over 15 years of rigorous evidence to draw lessons that can help colleges and policymakers as they work to improve college completion rates for low-income students.